Protein Alignment sm and ptbp2b

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001093477.1
• Gene: ptbp2b / 562434
• ZFINID: ZDB-GENE-060810-49
• Length: 538
• Species: Danio rerio
• Alignment Length: 554
• Identity: 137/554 - (24%)
• Similarity: 220/554 - (39%)
• Gaps: 143/554 - (25%)

  Fly    17 GGGATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQQNQQQALMNKSN--------------- 66
            |....|::.:|.....:..|.::.....|:.:...|||.......:..||
Zfish    78 GKVTNILMLKGKNQAFLELGTEEAAVTMVNYYTAVTPQVRNVPVFIQYSNHKELKTDSALNQRAQ 142

  Fly    67 ----------------DDLRRKRPETTRPNHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIF 115
                            .|:..|...|..|:.:|...|.|.|||:|:|||.:|....|.|::|:.|
Zfish   143 AVLQAVSAVQEGGSPSSDMASKSVLTPAPSPVLRIIIDNMFYPVTLDVLQQIFSKFGTVMKIITF 207

  Fly   116 KKNG-VQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNV-YKNEPDTSWDYTLST 178
            .||. .||:::|.:...|.:|:.:|:|.:||..||||:||::|...||| |.|  |.|.|||...
Zfish   208 TKNNQFQALLQFSDPVNAQQAKLSLDGQNIYNSCCTLRIDFSKLVNLNVKYNN--DKSRDYTRPE 270

  Fly   179 VKEIGNGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLV 243
            : ..|:|:.|:  :|...|.||.
Zfish   271 L-PAGDGQPPV--DPSMAAALSK------------------------------------------ 290

  Fly   244 APAQSHNLYQFKEPPLLG----------PGAAFP-PFGAPEYHTTTPENWKGAAIHPTGLMKEPA 297
                       ..|.|||          .|..|| ..||     .:|.:...||....|.:
Zfish   291 -----------DSPSLLGTPSGMVTSYSSGGGFPSSLGA-----ISPLSAAAAAAAAAGRV---- 335

  Fly   298 GVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQM 362
             .:.|.:.|          |.|::|..|:.:......||.|..:||:|.|:|.|..|:.:|::||
Zfish   336 -ALSGHSVP----------GGVLLVSNLNDEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQM 389

  Fly   363 GDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLP----DHSPSFKEYTGSKNNRF 423
            .|....:..:.|||...: .|..|::..||...:.       ||    |.....|::|.|..:||
Zfish   390 SDGNQAQLAMSHLNGQKM-YGKIIRVTLSKHQTVQ-------LPREGLDDQGLTKDFTSSPLHRF 446

  Fly   424 LSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATSVRLFPLKTERSSSGLIEFSN 488
            ..|...:...|.|||..||..|.|..:||:.|..:|:..   ..:|:.|....:|..| |::.:.
Zfish   447 KKPGSKNFQNIFPPSATLHLSNIPDNVTEEDLRLLFSNS---GGTVKAFKFFQDRKMS-LLQMAT 507

  Fly   489 ISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSS 522
            ..:|:.|::..::..: |:|.:    :::.||.|
Zfish   508 AEEAIQALIDLHNYDM-GRGHR----LRVSFSKS 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	36/86 (42%)
		RRM3_hnRNPL_like	319..390	CDD:240870	22/70 (31%)
		RRM4_hnRNPL_like	437..519	CDD:240873	19/81 (23%)
ptbp2b	NP_001093477.1	hnRNP-L_PTB	52..538	CDD:273733	137/554 (25%)
		RRM1_PTBP2	53..134	CDD:241222	10/55 (18%)
		RRM2_PTBP1_like	172..267	CDD:241137	41/96 (43%)
		RRM3_PTBP2	333..438	CDD:241140	32/127 (25%)
		RRM_SF	459..538	CDD:302621	23/87 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920