Protein Alignment sm and PABPC3

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_112241.2
• Gene: PABPC3 / 5042
• HGNCID: 8556
• Length: 631
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 94/516 - (18%)
• Similarity: 154/516 - (29%)
• Gaps: 191/516 - (37%)

  Fly    56 NQQQALMNKSNDDLRR----KRP-ETTRPNHILLFTIINPFYP-----ITVDVLHKICHPHGQVL 110
            |.:|..:.::...:.|    ||. |..:.:.|..:.::|.:..     |..:.|.|...|.|.:.
Human   257 NGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTIT 321

  Fly   111 RIVIFKKNGVQ---AMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNVYKNEPDTSW 172
            ...:..:.|..   ..|.|.:.:.||:|...:||..:......:.:...|.|:.....||    :
Human   322 SAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAYLTNE----Y 382

  Fly   173 DYTLSTVKEIGNGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQ-----QQPH 232
            ...:::|:.:.|.|:|    |......:.||.    |:|.......|....:.:|:     .:||
Human   383 MQRMASVRAVPNQRAP----PSGYFMTAVPQT----QNHAAYYPPSQIARLRPSPRWTAQGARPH 439

  Fly   233 PQHLHHQQQLVAPAQSHNLYQFKEPPLLGPGAAFPPFGAPEYHTTTPENWKGAAIHPT----GLM 293
            |                  :|.| |..:.|||...||.     |..|.:.:...:..|    ...
Human   440 P------------------FQNK-PSAIRPGAPRVPFS-----TMRPASSQVPRVMSTQRVANTS 480

  Fly   294 KEPAGVVPGRNAPVAFTPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTA 358
            .:..|..|...|..|.||      ||.                       .|.|.|:
Human   481 TQTVGPRPAAAAAAAATP------AVR-----------------------TVPRYKY-------- 508

  Fly   359 MVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLPDHSPSFKEYTGSKNNRF 423
                  |..|....||.|..|..|..::.:....|..|:
Human   509 ------AAGVRNPQQHRNAQPQVTMQQLAVHVQGQETLT-------------------------- 541

  Fly   424 LSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATSVRLFPLKTERSSSGLIEFSN 488
                 ||:....||.|            :.|::|           .|||||
Human   542 -----ASRLASAPPQK------------QKQMLG-----------ERLFPL-------------- 564

  Fly   489 ISQAVLAIMKCNHLPIEGKGTKFPFIMKLCFSSSKSMNGAWNNAASEGMIEKENEVDTKVD 549
                    ::..|..:.||.|.    |.|...:|:.:.          |:|....:.:|||
Human   565 --------IQAMHPTLAGKITG----MLLEIDNSELLY----------MLESPESLRSKVD 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	17/92 (18%)
		RRM3_hnRNPL_like	319..390	CDD:240870	11/70 (16%)
		RRM4_hnRNPL_like	437..519	CDD:240873	15/81 (19%)
PABPC3	NP_112241.2	PABP-1234	11..610	CDD:130689	94/516 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000