Protein Alignment sm and ptbp1a

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_001018313.1
• Gene: ptbp1a / 323490
• ZFINID: ZDB-GENE-050522-492
• Length: 574
• Species: Danio rerio
• Alignment Length: 611
• Identity: 143/611 - (23%)
• Similarity: 227/611 - (37%)
• Gaps: 210/611 - (34%)

  Fly     2 PY---NGASNGSGASGAGGGGATIVVTEGPQNKKIRTGVQQPGENDVHMHARSTPQ--------- 54
            ||   :||:||:                  .:||.:..::.||.....:|.|..|.
Zfish    46 PYIMSSGAANGN------------------DSKKFKGDIRSPGIPSRVIHVRKLPNDINEAEVIS 92

  Fly    55 --------------QNQQQALMNKSNDD--------------LRRKRP------------ETTRP 79
                          :.:.||.:..:.::              :.|..|            ....|
Zfish    93 LGLPFGKVTNLLMLKGKNQAFLEMNTEESAQTMVSYYSSVTPVIRNHPIFMQYSNHKELKTDNSP 157

  Fly    80 NH---------------------------------ILLFTIINPFYPITVDVLHKICHPHGQVLR 111
            |.                                 :|...:.|.|||:|:||||:|....|.||:
Zfish   158 NQVRAQAALQAVNAVQTGGMSLAAIDGAGMGSQSPVLRVIVENLFYPVTLDVLHQIFSKFGTVLK 222

  Fly   112 IVIFKKNG-VQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNV-YKNEPDTSWDY 174
            |:.|.||. .||:|::.:...|..|:.:|:|.:||..||||:|.::|...||| |.|  |.|.||
Zfish   223 IITFTKNNQFQALVQYSDGMTAQHAKLSLDGQNIYNACCTLRISFSKLTSLNVKYNN--DKSRDY 285

  Fly   175 TLSTVKEIGNGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQ 239
            |.   .::..|.|    :|.:.|
Zfish   286 TR---PDLPTGDS----QPSFDA------------------------------------------ 301

  Fly   240 QQLVAPAQSHNLYQFKEPPLLGPG--AAFPPFGAPEYHTTTPENW---KGAAIHPTGLMKEPAGV 299
            |.:.|.|            |..||  :|.|..||..:    |:.:   :.|.:...|:   |||.
Zfish   302 QTMAAAA------------LTAPGIISASPYAGAHGF----PQAFAIQQAAGLSLQGM---PAGA 347

  Fly   300 -----VPGRNAPVAFTPQG---------QAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKF 350
                 |||..|..|.....         .|..:|::|..|:.::.....||.|..:||:|.|:|.
Zfish   348 LASLSVPGAAAAAAAAAAAGRLGLSGLTAAGNSVLLVSNLNPESVTPQCLFILFGVYGDVMRVKI 412

  Fly   351 LKTKEGTAMVQMGDAVAVERCVQHLNNIPVGTGGKIQIAFSKQNFLSEVINPFLLP----DHSPS 411
            |..|:..|:|||.|....:..:.|||...: .|..::...||...:.       ||    :....
Zfish   413 LFNKKENALVQMSDGTQAQLAMSHLNGQKL-YGKALRATLSKHTTVQ-------LPREGHEDQGL 469

  Fly   412 FKEYTGSKNNRFLSPAQASKNRIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVPATSVRLFPLKT 476
            .|:|:.|..:||..|...:.:.|.|||..||..|.||.:|||.|.|:|........:.:.|  :.
Zfish   470 TKDYSNSPLHRFKKPGSKNYSNIFPPSSTLHLSNIPPSVTEDDLRGLFLSSGAVVKAFKFF--QK 532

  Fly   477 ERSSSGLIEFSNISQAVLAIMKC-NH 501
            :|..: ||:.:::.:|:.:::|. ||
Zfish   533 DRKMA-LIQLASVEEAIESLIKFHNH 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	37/119 (31%)
		RRM3_hnRNPL_like	319..390	CDD:240870	22/70 (31%)
		RRM4_hnRNPL_like	437..519	CDD:240873	21/66 (32%)
ptbp1a	NP_001018313.1	hnRNP-L_PTB	72..574	CDD:273733	133/567 (23%)
		RRM1_PTBP1	74..154	CDD:241221	7/79 (9%)
		RRM2_PTBP1_like	191..286	CDD:241137	41/96 (43%)
		RRM3_PTBP1	381..473	CDD:241139	27/99 (27%)
		RRM_SF	494..574	CDD:302621	22/67 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920