Protein Alignment sm and Hnrnpll

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_233805.5
• Gene: Hnrnpll / 313842
• RGDID: 1305861
• Length: 591
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 182/480 - (37%)
• Similarity: 253/480 - (52%)
• Gaps: 90/480 - (18%)

  Fly    58 QQALMNKSNDDLRRKRPETTRP----NHILLFTIINPFYPITVDVLHKICHPHGQVLRIVIFKKN 118
            |||..|.|... |..||..|..    |.:||.:|.||.||||||||:.:|:|.|:|.||||||:|
  Rat   190 QQAFFNYSTSK-RITRPGNTDDPSGGNKVLLLSIQNPLYPITVDVLYTVCNPVGKVQRIVIFKRN 253

  Fly   119 GVQAMVEFDNLDAATRARENLNGADIYAGCCTLKIDYAKPEKLNVYKNEPDTSWDYTLSTVKEIG 183
            |:||||||:::..|.:|:..|||||||||||||||:||:|.:|||.:|:.| |||||
  Rat   254 GIQAMVEFESVLCAQKAKAALNGADIYAGCCTLKIEYARPTRLNVIRNDND-SWDYT-------- 309

  Fly   184 NGRSPLLQEPLYVATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLVAPAQS 248
               .|.|.                       |:.:.:..|:||.... ||....|.
  Rat   310 ---KPYLG-----------------------RRDRGKGRQRQAILGD-HPSSFRHD--------- 338

  Fly   249 HNLYQFKEPPLLGPGAAFPPFGAPEYH----TTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAF 309
                        |.|:..|....|..:    ..|||           |:..|   :|  .|..::
  Rat   339 ------------GYGSHGPLLPLPSRYRMGSRDTPE-----------LVAYP---LP--QASSSY 375

  Fly   310 TPQGQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQH 374
            ...|...|:|:||.||.....|..::|||.|||||:.::||:||..|||:|:|||..||||.|.|
  Rat   376 MHGGSPSGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTH 440

  Fly   375 LNNIPVGTGGKIQIAFSKQNFL--SEVINPFLLPDHSPSFKEYTGSKNNRFLSPAQASKNRIQPP 437
            |||:.: .|.::.:..|||:.:  |::   |.|.|.:.|:|::..||||||.|..|||||.||||
  Rat   441 LNNVKL-FGKRLNVCVSKQHSVVPSQI---FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPP 501

  Fly   438 SKILHFFNTPPGLTEDQLIGIFNIKDV-PATSVRLFPLK-TERSSSGLIEFSNISQAVLAIMKCN 500
            |.:||::|.|..:||:....:.|..:| |....::|..| :.::.|||:|:...:.||.|:...|
  Rat   502 SCVLHYYNVPLCVTEETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALN 566

  Fly   501 HLPIEGKGTKFPFIMKLCFSSSKSM 525
            |..|.......|:.:|||||:|..:
  Rat   567 HYQIRVPNGSNPYTLKLCFSTSSHL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	55/84 (65%)
		RRM3_hnRNPL_like	319..390	CDD:240870	35/70 (50%)
		RRM4_hnRNPL_like	437..519	CDD:240873	26/83 (31%)
Hnrnpll	XP_233805.5	RRM1_hnRPLL	122..205	CDD:241225	6/15 (40%)
		hnRNP-L_PTB	123..590	CDD:273733	182/477 (38%)
		RRM2_hnRPLL	214..309	CDD:241230	60/95 (63%)
		RRM3_hnRPLL	385..455	CDD:241144	35/70 (50%)
		RRM4_hnRPLL	501..585	CDD:241149	26/83 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343589
Domainoid	1	1.000	117	1.000	Domainoid score	I5760
eggNOG	1	0.900	-	-		E1_KOG1456
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2637
OMA	1	1.010	-	-		QHG48602
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	1	1.000	-	-		FOG0002729
OrthoInspector	1	1.000	-	-		otm46151
orthoMCL	1	0.900	-	-		OOG6_104479
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1821
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.670