Protein Alignment sm and PABPC1

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: NP_002559.2
• Gene: PABPC1 / 26986
• HGNCID: 8554
• Length: 636
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 76/416 - (18%)
• Similarity: 126/416 - (30%)
• Gaps: 119/416 - (28%)

  Fly   124 VEFDNLDAATRA-----RENLNGADIYAGCCTLKID----------------YAKPEKLNVYKNE 167
            |.|:..:.|.:|     .:.|||..||.|....|::                ..:.:.:|:|...
Human   236 VSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN 300

  Fly   168 PDTSWD-----------YTLSTVKEIGNG-----------RSP--------------LLQEPLYV 196
            .|...|           .|:::.|.:..|           .||              :..:||||
Human   301 LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV 365

  Fly   197 ATLSTPQQHVSHQHHHHLRQQQQQQHQQQAPQQQPHPQHLHHQQQLVAPAQSHNLYQFKEPPLLG 261
            |.....::..:     ||..|..|  :..:.:..|:|....:|     ||.....:....|....
Human   366 ALAQRKEERQA-----HLTNQYMQ--RMASVRAVPNPVINPYQ-----PAPPSGYFMAAIPQTQN 418

  Fly   262 PGAAFPPFGAPEYHTTTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFT--PQGQAQGAVMMVYG 324
            ..|.:||....:...:.....:||..||  ....|..:.|....|...|  |.......||....
Human   419 RAAYYPPSQIAQLRPSPRWTAQGARPHP--FQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQR 481

  Fly   325 LDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQHLNNIP--------VG 381
            :.:.::.|        :....|......|.....:.|...|..|....||||..|        |.
Human   482 VANTSTQT--------MGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVH 538

  Fly   382 TGGKIQIAFS---------KQNFLSEVINPFLLPDHSPSFKEYTG---SKNNRFLSPAQASKNRI 434
            ..|:..:..|         ::..|.|.:.|.:...|.....:.||   ..:|
Human   539 VQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDN------------- 590

  Fly   435 QPPSKILHFFNTPPGLTE--DQLIGI 458
               |::||...:|..|..  |:.:.:
Human   591 ---SELLHMLESPESLRSKVDEAVAV 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	12/61 (20%)
		RRM3_hnRNPL_like	319..390	CDD:240870	15/78 (19%)
		RRM4_hnRNPL_like	437..519	CDD:240873	6/24 (25%)
PABPC1	NP_002559.2	PABP-1234	11..615	CDD:130689	76/416 (18%)
		CSDE1-binding	166..289		11/52 (21%)
		(Microbial infection) Binding to HRSV M2-1 protein. /evidence=ECO:0000269|PubMed:31649314	541..636		15/89 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000