Protein Alignment sm and Hnrnpl

DIOPT Version :9

• Sequence 1: NP_001246428.1
• Gene: sm / 37254
• FlyBaseID: FBgn0003435
• Length: 552
• Species: Drosophila melanogaster
• Sequence 2: XP_006539619.1
• Gene: Hnrnpl / 15388
• MGIID: 104816
• Length: 623
• Species: Mus musculus
• Alignment Length: 612
• Identity: 209/612 - (34%)
• Similarity: 292/612 - (47%)
• Gaps: 157/612 - (25%)

  Fly     5 GASNGSGASGAGGG------------------------------------GATIVVTEGPQNKKI 33
            |...||||:|.|||                                    |....|...|:.::.
Mouse    73 GGGGGSGAAGGGGGENYDDPHKTPASPVVHIRGLIDGVVEADLVEALQEFGPISYVVVMPKKRQA 137

  Fly    34 R----------TGVQQPGENDVHM--HARSTPQQNQQQALMNKSNDDLRRKRPETTRPNHILLFT 86
            .          ..|....:|.:::  |.........|:......:||.|       ..|.:||||
Mouse   138 LVEFEDVLGACNAVNYAADNQIYIAGHPAFVNYSTSQKISRPGDSDDSR-------SVNSVLLFT 195

  Fly    87 IINPFYPITVDVLHKICHPHGQVLRIVIFKKNGVQAMVEFDNLDAATRARENLNGADIYAGCCTL 151
            |:||.|.||.|||:.||:|.|.|.|||||:|||||||||||::.:|.||:.:|||||||:|||||
Mouse   196 ILNPIYSITTDVLYTICNPCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTL 260

  Fly   152 KIDYAKPEKLNVYKNEPDTSWDYTLSTVKEIGN-GRSPLLQEPLYVATLSTPQQHVSHQHHHHLR 215
            ||:||||.:|||:||:.|| ||||...:...|: |.:|
Mouse   261 KIEYAKPTRLNVFKNDQDT-WDYTNPNLSGQGDPGSNP--------------------------- 297

  Fly   216 QQQQQQHQQQAPQQQPHPQHLHH--------QQQLVAPAQSHNLYQFKEP----PLLGPGAAFPP 268
                .:.|:|.|....||.....        .:...|||:       :.|    |:|....:.||
Mouse   298 ----NKRQRQPPLLGDHPAEYGEGRGFPSVDSRGSCAPAR-------RPPRKFSPVLPLFPSHPP 351

  Fly   269 FGAPE--YHT--------TTPENWKGAAIHPTGLMKEPAGVVPGRNAPVAFTPQ----------- 312
             |.|.  ||:        ..|.:::|..:.|      |.|  ..|..|..:.||
Mouse   352 -GGPHGGYHSHYHDEGYGPPPPHYEGRRMGP------PVG--GHRRGPSRYGPQYGHPPPPPPPP 407

  Fly   313 ---GQAQGAVMMVYGLDHDTSNTDKLFNLVCLYGNVARIKFLKTKEGTAMVQMGDAVAVERCVQH 374
               ..|...|:||||||....|.|::||:.||||||.::||:|:|.|.|||:|.|..||:|.:.|
Mouse   408 DYGPHADSPVLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITH 472

  Fly   375 LNNIPVGTGGKIQIAFSKQNFLSEVINPFLLP-------DHSPSFKEYTGSKNNRFLSPAQASKN 432
            ||| ....|.|:.:..|||        |.::|       |.|.|:|:::.|:||||.:|.||:||
Mouse   473 LNN-NFMFGQKMNVCVSKQ--------PAIMPGQSYGLEDGSCSYKDFSESRNNRFSTPEQAAKN 528

  Fly   433 RIQPPSKILHFFNTPPGLTEDQLIGIFNIKDVP-ATSVRLFPLKTERSSSGLIEFSNISQAVLAI 496
            |||.||.:|||||.|..:||:....|.:...|. .|||::|..|:|||||||:|:.:.|.|:..:
Mouse   529 RIQHPSNVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETL 593

  Fly   497 MKCNHLPIEGKGTKFPFIMKLCFSSSK 523
            ...||..::.....:|:.:|||||:::
Mouse   594 GFLNHYQMKNPNGPYPYTLKLCFSTAQ 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sm	NP_001246428.1	RRM2_hnRNPL_like	80..165	CDD:241138	59/84 (70%)
		RRM3_hnRNPL_like	319..390	CDD:240870	36/70 (51%)
		RRM4_hnRNPL_like	437..519	CDD:240873	32/82 (39%)
Hnrnpl	XP_006539619.1	hnRNP-L_PTB	97..621	CDD:273733	200/588 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839749
Domainoid	1	1.000	117	1.000	Domainoid score	I5889
eggNOG	1	0.900	-	-		E1_KOG1456
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1174
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2705
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48602
OrthoDB	1	1.010	-	-		D1545178at2759
OrthoFinder	1	1.000	-	-		FOG0002729
OrthoInspector	1	1.000	-	-		otm44061
orthoMCL	1	0.900	-	-		OOG6_104479
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10802
SonicParanoid	1	1.000	-	-		X1821
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.700