Protein Alignment TTLL6A and Ttll4

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_001414011.1
• Gene: Ttll4 / 690512
• RGDID: 1594742
• Length: 1198
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 172/659 - (26%)
• Similarity: 280/659 - (42%)
• Gaps: 172/659 - (26%)

  Fly   162 NIQWSDSTPHH---DLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMF-PGDYRIFPKTWL 222
            |..|.....||   ...|:::..|::|||||..:|.|||.|.|||:||...| ..::..||::::
  Rat   632 NDDWLGCWGHHMKSPGFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFI 696

  Fly   223 MPTDAYDV-AIYANKHKRTFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKF 286
            :|.|:..: ..:.:..::.:|:||.::.:|.||.:......:.||..|:.|.|:.:|.||.|.||
  Rat   697 LPQDSKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKF 761

  Fly   287 DLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVGNGPE 351
            |||:|..|||.|||||:::::||.|||:.||.|.....| |.|||||||.:|::|::|. .|..|
  Rat   762 DLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLS-NKFMHLTNYSVNKKNAEYQ-ANADE 824

  Fly   352 A---GSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISAWP----TLKHNYNVCFPKHDKIQ 409
            .   |.|..|.|...:|.....:....|..:.|.::||:||:.|    .||......:..|
  Rat   825 TACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCH---- 885

  Fly   410 ASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNMLSTALVDKEQIIRDD 474
               :|.||||::|..|||::||||.:|||.::..:|:.:|..:|||.||:....|.:.|.|:...
  Rat   886 ---ELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGFVLPNMEDILSSS 947

  Fly   475 RT-----------------------EH--RARLLRNIYNKKAAAQMPGYSSPIREVGGHDVRQAC 514
            .:                       ||  ..::.:..|..:.......|||.:..:...|||
  Rat   948 SSPSSSSGSSTSLPSSPREKCQMTPEHFTAQKMKKAYYLTQKVPDQDFYSSVLDVLTPDDVR--- 1009

  Fly   515 SIGALTQQIAWEESHLGNYRRIMPPRDSSKVNYYCKFYEQNKQPMFADTVASRRREQLNLQAIQK 579
                :..::..|.|..|.:.||.|.|.||:   |.:|:|   ||.:.:.        |..|..||
  Rat  1010 ----VLVEMEDEFSRRGQFERIFPSRISSR---YLRFFE---QPRYFNI--------LTTQWEQK 1056

  Fly   580 HQRERQQ--DLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNPVILQSRRRREEAEAYAKKHRAL 642
            :...:.:  ||::                .|                         .|...|..:
  Rat  1057 YHGNKLKGVDLLR----------------NW-------------------------CYKGFHTGI 1080

  Fly   643 IAREIQRQKEQLLAPTCAKERLGIWQ---SVRREKRSQFSPKRGSSITKAYRRKQQRNLSLRARQ 704
            ::..         ||        :|.   |:....:...:|   ::::::...|.::
  Rat  1081 VSDS---------AP--------LWSLPTSLMNASKGDGTP---NAVSRSDHNKSRK-------- 1117

  Fly   705 QRMIEMEAQRDAKFLEQHAQKQRLEGGRKTGQSESP-------NLLSKITAKSK----TSLKKKM 758
                                |...||..:.|.:..|       :.:|:.|..||    ||.:.|.
  Rat  1118 --------------------KSCSEGNSEDGPTSKPKKSQAGLSPISRKTLSSKNNENTSKQSKR 1162

  Fly   759 KPKGKPELK 767
            ..:|.|.||
  Rat  1163 STQGLPVLK 1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	112/298 (38%)
Ttll4	NP_001414011.1	None