Protein Alignment TTLL6A and ttll7

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_009304088.2
• Gene: ttll7 / 565243
• ZFINID: ZDB-GENE-070112-2112
• Length: 917
• Species: Danio rerio
• Alignment Length: 821
• Identity: 222/821 - (27%)
• Similarity: 382/821 - (46%)
• Gaps: 140/821 - (17%)

  Fly   138 TRFQLVAKVTRNMGFQHV-PEHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEICRKDLLSR 201
            |::::|..|...:.|... .:....|:.|:||...|:.:..::.:|:|||||||.||||||.|:|
Zfish    50 TKYEIVRIVIEELTFHKARDDDETANLIWNDSAVQHEKIAELRNYQRINHFPGMGEICRKDCLAR 114

  Fly   202 NLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYANKHKR-----TFILKPYSAGQGRGIWITTDLR 261
            |:.:|:|..|.:|...||||:.|.:......|..:.||     |||:||.:...|.||.:..:..
Zfish   115 NMAKMIKSQPQEYSFIPKTWIFPAECTQFQNYVKELKRKGKQKTFIVKPANGAMGHGISLIRNCE 179

  Fly   262 TVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSH 326
            .:..::..|.|.|:::|.|::|||||||.|.||||.||||:|:||:||.|..|:||..|...|.:
Zfish   180 KLPVQDHFIVQEYLDKPFLMEGYKFDLRFYILVTSCDPLRVFLYNDGLVRMGTEKYHTPNESNLN 244

  Fly   327 NVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISAW 391
            .::||||||.:|:.|..:......:.||||.:..|.::|..::|||.:||..|.:.::|||:.|.
Zfish   245 QLYMHLTNYSVNKHNENFERDETVDKGSKRSIGWFTEFLRINDYDVAKFWGDVSELVVKTLLVAE 309

  Fly   392 PTLKHNYNVCFPKHDKIQAS--FQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIR 454
            |.:.|.|.:|.|......||  |::|||||::|.||||::||:|..||...|:.:|.:||:..:.
Zfish   310 PHVLHAYRMCRPGQPPGSASVCFEVLGFDIILDRKLKPWLLEINRAPSFGTDQKIDYDVKKGALL 374

  Fly   455 DTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGYSSP------IREVGGHDVRQA 513
            :.|.:|:....||    |.:..:.:|...|.:|.:.:..::...||.      :.|....::::
Zfish   375 NALKLLNIRASDK----RRNLAQQKAEAQRRLYGQGSMRKLTAGSSEWEKQRHLLERRREELKE- 434

  Fly   514 CSIGALTQQIA---WEESHLGNYRRIMPPRDSSKVNYYCKFYEQNKQPMFADTVASRRREQLNLQ 575
             .:..:.:|::   .|:.||||||||.||.|...:..|........|...|...||.::|..|
Zfish   435 -RLAQVRKQVSRDEHEKRHLGNYRRIYPPDDKLLLEKYESLLSAAFQTFLAGRAASLQKEMNN-- 496

  Fly   576 AIQKHQRERQQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNPVILQS--------RRRREEA 632
            .:::.:.|...||::|.::  ..:..|||         ..:|..|.:|.|        |..|:..
Zfish   497 PLKRMKEEDILDLLEQCEL--DDEKLMGK---------TSKQKGPKVLSSMPESSPVPRGHRDPE 550

  Fly   633 EAYAKKHRALIAREIQRQKEQLLAPTCAKERLG--------IWQSVRRE--------------KR 675
            ::.|....:..|.:...:.|   :.:..:|:|.        .|:...:.              :|
Zfish   551 DSSASCSDSSSASDADGEDE---SSSIMQEKLNRPERSSRVHWKPAPKPVRGPSSSPYLSGLIRR 612

  Fly   676 SQFSPKRGSSITKAYRRKQQRNLSLRARQQRMIEMEAQRDAKFLEQ------H--AQKQRLEGGR 732
            |...|:..||:|......:.|......:....:...|.:.|..:.|      |  ::.|.|....
Zfish   613 SMSCPRSISSLTAQSPTNESRQPKTATQMANTMTAAATQTAATMMQMTPVRPHTASRSQSLSRNC 677

  Fly   733 KTGQ---SESPNLLSKITAKSKTSLKKKMKPKGKPELKKETLQEGNHCQMTKSKVELTPGSKARA 794
            .|.:   |.|...:...:|:.:|.|.|:.    :.||.::||     ..:.:.::.....|:..|
Zfish   678 STNRVPHSSSLGAIHPNSAQGETPLSKEQ----EAELMQQTL-----TALGEMRIRYPGKSEEEA 733

  Fly   795 FANWTARTINEAETDQLL-SWRKERAN-------QLNETRLRELIFSKMYENGHLTKNDIKCF-- 849
                      ||..|::| :|:..:..       :|:.|:.|:::        .:.:.:|:..
Zfish   734 ----------EAMLDEILNNWKYHKPKVASYWLVKLDATKQRKVL--------DIVRTNIRSVLQ 780

  Fly   850 -----PDL----LYQILNN--------------DCKEASSR 867
                 ||:    ||::.|.              :|...|.|
Zfish   781 RIWSEPDVESLRLYRLFNRVFNRLLWSHGQGLWNCLSTSGR 821

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	124/296 (42%)
ttll7	XP_009304088.2	None