Protein Alignment TTLL6A and TTLL4A

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_723642.2
• Gene: TTLL4A / 47729
• FlyBaseID: FBgn0026147
• Length: 1071
• Species: Drosophila melanogaster
• Alignment Length: 695
• Identity: 181/695 - (26%)
• Similarity: 291/695 - (41%)
• Gaps: 179/695 - (25%)

  Fly     3 SKKSPRPTYCEPNPYTRFFNAHK----SLPPDKNGQKQEI-YNRESVYVLSNKSRGKRRSGRENN 62
            |.|.|.||            .|:    |....:.|:||:. ..|.||...|:|..|   :|.|..
  Fly   392 STKKPMPT------------VHRVLLYSTQSPRLGRKQQFSTQRLSVKQQSSKVLG---AGDERQ 441

  Fly    63 -----QPTWRR----------RGGGVNED---------------------------HIMVVTQ-- 83
                 :|..::          |....:||                           |...:|.
  Fly   442 TVLLLEPEHKQEDHRSAIDFDRNDDFDEDDDLDNLSNFDESDTASVLSDTEDGYRAHAFKLTHSV 506

  Fly    84 DNTQQQRDKPLLTASQLDSICYDVIKEPP--------------MQFHVN---GTDIVPSI-RGLR 130
            |.....:..|...:||...   |.:|.|.              :.|..|   |..:.|.: |.|:
  Fly   507 DRFSSPQSTPSFLSSQSSE---DDLKNPDSLLVPSLFPYVPPYLSFSSNTKRGPRVPPDLHRVLK 568

  Fly   131 LSVCVEHTRFQLVAKVTR----NMGFQHVPEHRLWNIQWSD--STPHHDLLRNMKRFQQINHFPG 189
            ..:.      .::.||.|    |.|.:.:.:...|...|..  .:|....:|:   :|:|||.||
  Fly   569 WRIT------NIMPKVVRLILANSGMRMLKKTNDWMGVWGKHLKSPCFKAIRS---YQKINHLPG 624

  Fly   190 MVEICRKDLLSRNLNRML-KMFPGDYRIFPKTWLMPTDAYDV----AIYANKHKRTFILKPYSAG 249
            ...|.|||...:||.|.: |....::...|:|:::|.|...:    ..||.::.: :|:||.::.
  Fly   625 SFRIGRKDSCWKNLQRQMGKHSNKEFGFMPRTYIIPNDLGALRRHWPKYAQRNTK-WIIKPPASA 688

  Fly   250 QGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFAT 314
            :|.||.:......:.||..||.|.||||||||:|.|||||:|.|||||:|||:|:|:.||||||:
  Fly   689 RGAGIRVINRWGQIPKRRPLIVQKYIERPLLINGSKFDLRLYVLVTSVNPLRVFMYHNGLARFAS 753

  Fly   315 QKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVGNGPEA--GSKRKLSAFNKWLVDHNYDVGEFWA 377
            .|| ...|...::..||||||.:|:.:|.|.......|  |.|..:.:...:|.:........|.
  Fly   754 VKY-SAKTDTLNDRCMHLTNYSINKFSSNYSKNEDVNACHGHKWTIKSLWTYLANRGVRTDCLWE 817

  Fly   378 SVDDAIIKTLISAWPTLKHNYNVCFPKHDKIQAS-FQLLGFDILVDWKLKPYILEVNHTPSLSAD 441
            ::...:::|:::.    ::..|.....:.:.:.| |:|.|||:::|..|.|::||||.:|||.::
  Fly   818 ALRSLVLRTILAG----ENGINSMIRANVESKYSCFELFGFDVILDSDLVPWLLEVNISPSLHSE 878

  Fly   442 ESVDMEVKRPLIRDTLNMLSTAL--------VDKEQ------------------------IIRDD 474
            ..:|..||.||::..||   |||        :||::                        :.|::
  Fly   879 LPLDAHVKAPLVQGVLN---TALYNVPPKLSLDKQKELAAEFSFPPGTQMCYDKRLYINYLSREE 940

  Fly   475 RTEHRARLLRNIYNKKAAAQMPGYSSPI-REVGGHDVRQACSIGALTQQIAWEE-SHLGNYRRIM 537
            :.:|      |.:.:|:......|...| ..:...|||  |.|      ||.:| :......||.
  Fly   941 KIKH------NTFTRKSMEDRNEYVDAILNNLTPDDVR--CLI------IAEDELARCAPLERIF 991

  Fly   538 PPRDSSKVNYYCKFYEQNKQPMFADTV--------ASRRREQLNL 574
            |...:.|   |.|:   |..|.:.:.:        |:.|.|.:.|
  Fly   992 PTDQTHK---YLKY---NDTPRYYNRLLDAWESRYANNRTEGIAL 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	109/329 (33%)
TTLL4A	NP_723642.2	TTL	614..909	CDD:397308	108/306 (35%)