Protein Alignment TTLL6A and TTLL6B

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_651549.1
• Gene: TTLL6B / 43282
• FlyBaseID: FBgn0039501
• Length: 720
• Species: Drosophila melanogaster
• Alignment Length: 825
• Identity: 339/825 - (41%)
• Similarity: 447/825 - (54%)
• Gaps: 212/825 - (25%)

  Fly    54 KRRSGR----ENNQPTWRRRGGGVNEDHIMVVTQDNTQQQRDKPLLTASQLDSICYDV-----IK 109
            |||:..    ::|.|.:....|           :::.....:..|....||::..|.|     :.
  Fly    76 KRRTAADKQVDDNSPYYGPSSG-----------ENSPMPAEEAKLQGFIQLNNKTYRVECPTRVL 129

  Fly   110 EPPMQFHVNGTDIVPSIRGLRLSVCVEHTRFQLVAKVTRNMGFQHVPEHRLWNIQWSDSTPHHDL 174
            .|||    |..:..|:.. .:.::||.::|:.::.|:::.:|::.|.|.::|||.||||.|..:|
  Fly   130 NPPM----NVDEERPASE-TKSTICVSNSRYAMIGKISKTLGYKLVKESKMWNILWSDSFPGVEL 189

  Fly   175 LRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYANKHKR 239
            .:||||||||||||||:|||||||||||||||||:||.||:||||||::|.|..|...||..|||
  Fly   190 FKNMKRFQQINHFPGMIEICRKDLLSRNLNRMLKIFPQDYKIFPKTWMLPADYGDAMNYALNHKR 254

  Fly   240 TFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFV 304
            ||||||.|..||||||:|.||:|:|..|:|||||||.|||||||||||||||||:||||||||||
  Fly   255 TFILKPDSGAQGRGIWLTNDLKTIGPHERLICQTYIHRPLLIDGYKFDLRVYTLITSVDPLRIFV 319

  Fly   305 YNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNKWLVDHN 369
            ||||||||||.|||.||.||:::::||||||.:|:|||.|.:.:..:.||||||||.|.|:..||
  Fly   320 YNEGLARFATNKYVEPTPGNANDLYMHLTNYSVNKRNSHYELCDNDDCGSKRKLSAINNWMRRHN 384

  Fly   370 YDVGEFWASVDDAIIKTLISAWPTLKHNYNVCFPKHDKIQASFQLLGFDILVDWKLKPYILEVNH 434
            |||.|||::|||.||||::||||.|||||:.|||.||||||.|::||||||||||||||||||||
  Fly   385 YDVEEFWSNVDDVIIKTVLSAWPVLKHNYHACFPGHDKIQACFEILGFDILVDWKLKPYILEVNH 449

  Fly   435 TPSLSADESVDMEVKRPLIRDTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMP--- 496
            :||...:|.||.||||||||||||::||.|.||.||:::||...:.|||:  .......|.|
  Fly   450 SPSFHTNEQVDREVKRPLIRDTLNLVSTVLADKRQILKEDRKRVKQRLLK--IRGDPPVQRPRLG 512

  Fly   497 -GYSSP--IREVGGHDVR------QACSIGALTQQIAWEESHLGNYRRIMPPRDSSKVNYYCKFY 552
             |.|.|  ..:.|..|.:      :|...|.|.||||||||||||:|:||||.|.||::||.:||
  Fly   513 GGTSKPKIDAQKGSPDAQPVDVEPEAEDHGPLAQQIAWEESHLGNFRKIMPPPDLSKLDYYTRFY 577

  Fly   553 EQNKQ-PMFADTVASRRREQLNLQAIQKHQRERQQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGE 616
            .|:.| .:||:|.||::||.|
  Fly   578 AQSHQVSIFAETAASKKREDL-------------------------------------------- 598

  Fly   617 QVNPVILQSRRRREEAEAYAKKHRALIAREIQRQKEQLLAPTCAKERLGIWQSVRREKRSQFSPK 681
                                       ||:::.|.|                    ||
  Fly   599 ---------------------------ARKMRIQLE--------------------EK------- 609

  Fly   682 RGSSITKAYRRKQQRNLSLRARQQRMIEMEAQRDAKFLEQHAQKQRLEGGRKTGQSESPNLLSKI 746
                               :|:||:|:..:|:|||:
  Fly   610 -------------------KAKQQQMLNGKAKRDAR----------------------------- 626

  Fly   747 TAKSKTSLKKKMKPKGKPELKKETLQEGNHCQMTKSKVELTPGSKARAFANWTARTINEAETDQL 811
              |..|.|        .|...:|           |:::..     .|...||:...|::||....
  Fly   627 --KRHTVL--------LPRAVRE-----------KNRINF-----FRLRENWSPGFISDAEERLR 665

  Fly   812 LSWRKERANQLNETRLRELIFSKMYENGHLTKNDIKCFPDLLYQI 856
            .:|...||..:...::.|.|:|.:||.|.||..|:..:|.|.:.:
  Fly   666 HTWLHMRAEAIRTLKITENIYSNLYETGLLTNTDMVVYPHLYHNL 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	213/289 (74%)
TTLL6B	NP_651549.1	TTL	196..486	CDD:397308	213/289 (74%)