Protein Alignment TTLL6A and TTLL3A

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_609069.1
• Gene: TTLL3A / 33947
• FlyBaseID: FBgn0031854
• Length: 992
• Species: Drosophila melanogaster
• Alignment Length: 818
• Identity: 181/818 - (22%)
• Similarity: 304/818 - (37%)
• Gaps: 217/818 - (26%)

  Fly    95 LTASQLDSICYDVIKEPPMQFHVNGTDIVPSIRGLRLSVCVEHTRFQLVAKVT----RNMGFQHV 155
            |||      |...::....::|..|:|.|.|..|......::....:||..:.    .::.|:..
  Fly   297 LTA------CVAFLRAMLCKYHKQGSDAVFSCSGKIPYSAIDFAYKRLVEYIDSCQHNDIDFEDP 355

  Fly   156 PEHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPG-----MVEICRKDLLSRNLNRMLKMFPGDYR 215
            |  ::|...|......|..|.|  ...:|.|..|     ||:.|    ||. :::|...:|
  Fly   356 P--KIWEHDWDAFLFQHQQLVN--EDGRIQHDGGQRLEPMVKSC----LSL-VDKMKVHWP---- 407

  Fly   216 IFPKTWLMPTDAYDVAIYANKHKRTFILKPYSAGQGRGIWITTDLR--------TVGKREKLICQ 272
                       .|.:..|.|    .:|:||.:..:||||.:..:|:        ::..:.:.:.|
  Fly   408 -----------QYSLDGYQN----MWIVKPANKCRGRGIILMDNLKKILGVVNLSIASKSRYVVQ 457

  Fly   273 TYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCL 337
            .||||||::...|||:|.:.|:|:..||.::.|.|...||::|:|    :.::|:..:|||||.:
  Fly   458 KYIERPLILFQTKFDIRQWFLITNTQPLVVWFYRESYLRFSSQEY----SLSNHHESVHLTNYAI 518

  Fly   338 NRRNSQYMVGNGPEAGSKRKLSAFNKW-----------LVDHNYDVGEFWASVDDAIIKTLISAW 391
            .::.:     ||..   .::|.:.|.|           :..:|..:...:..:..||:..::::.
  Fly   519 QKKYT-----NGKR---DKRLPSENMWDCYSFQAYLRQIGKYNMWLERIFPGMRKAIVGCMLASQ 575

  Fly   392 PTLKHNYNVCFPKHDKIQASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDT 456
            ..:           |:...:|:|.|.|.::.....|:::|:|.:|.|.|..||           |
  Fly   576 ENM-----------DRRPNTFELFGADFMICENFYPWLIEINSSPDLGATTSV-----------T 618

  Fly   457 LNMLSTALVDKEQIIRDDRTEHRARLLR-NIYNKKAAAQMPGYSSPIREVGGHDVRQACSIGA-- 518
            ..|....|.|..:::.|.||:.:|.|.. .:..::.....|.|......|.|..|.|..:.|.
  Fly   619 ARMCPQCLEDVVKVVIDRRTDPKAELGNFELAYRQVVPPTPAYMGLNLFVKGKQVLQKANHGGGH 683

  Fly   519 ---LTQQIAWEESHLGN--YRR----IMPPRDSSKVNYYCKFYEQNKQPMFADT---------VA 565
               ..||...|.|...:  ||:    |.|....|:::        ...|.|..|         ..
  Fly   684 GHYYYQQQRKERSLATSSVYRQRSAIIHPATSISRIH--------RAMPTFNATEYMEKYMVEPL 740

  Fly   566 SRRREQLNLQAIQKHQRE----------RQQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNP 620
            |..|..|..|..||....          .....|.:|...:..|.....|.|..|..:.||||..
  Fly   741 SSSRSSLCSQLPQKSPSAAPALTATPSGATSSYILKQAGRSITQLLSATHKRNTGGSLSGEQVQS 805

  Fly   621 VILQSRRRR---------EEAEAYAKKHRALIAREIQRQKEQL----------LAPTCAKERLGI 666
            ..|..:|:|         ...|:..||.:.||........|.:          ...|...||.
  Fly   806 TALPPKRQRSCGPRLSSTNPVESTEKKFKILIKNYSSNGNENMQDARPEVANSATATAISERK-- 868

  Fly   667 WQSVRREKRSQFSPKRGSSITKAYRRKQQRNL---SLRARQQRMIEMEAQRDAKFLEQHAQKQRL 728
            |:|:|     ..:...|.|...|.|.|....:   ||..|  |:...:::.|:..:  ||.
  Fly   869 WRSLR-----NIAATAGGSSNLAARSKGPPLIAPPSLPTR--RLTRTKSEIDSTGM--HAI---- 920

  Fly   729 EGGRKTG-QSESPNLLSKITAKSKTSLKKKMKPKGKP---ELKKETLQEGNHCQMTKSKVELTPG 789
              ||..| :|..|.|        ..|:..:...:|:|   .||:.|           |:::|:..
  Fly   921 --GRTFGRKSNGPRL--------PISISVQALHRGEPIVAALKQAT-----------SELQLSQA 964

  Fly   790 SKARAFANWTARTINEAETDQLLSWRKERANQLNETRL 827
                                |::|.|...||:||.:.|
  Fly   965 --------------------QMMSPRTALANKLNGSTL 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	73/313 (23%)
TTLL3A	NP_609069.1	TTL	342..640	CDD:397308	83/359 (23%)