Protein Alignment TTLL6A and Ttll8

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_056840443.1
• Gene: Ttll8 / 315214
• RGDID: 1306462
• Length: 927
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 150/717 - (20%)
• Similarity: 256/717 - (35%)
• Gaps: 239/717 - (33%)

  Fly     9 PTYCEPNPYTRFFNAHKSLPPDKNGQKQEIYN--RESV------YVL-----SNKSRGK-RRSGR 59
            |.|.:.||.| ||.....|..:  .:|||..:  |.:|      :|:     .|:::|| ::...
  Rat   321 PWYVQANPNT-FFPRCYGLCTE--SEKQEFLDDFRRTVAASILKWVVHHQNYCNRAKGKSKKEEA 382

  Fly    60 ENNQPTWRRRGGGVNEDHIMVVTQDNTQQQRDKPLLTASQLDSICYDVIKEPPMQFHVNGTDIVP 124
            :|..|:.::               |........|.|:...:|:.|
  Rat   383 KNGDPSPKK---------------DPDNPDLKLPSLSGQVVDTAC-------------------- 412

  Fly   125 SIRGLRLSVC------VEHTRFQLVAKVTRNMGFQHVPEHRLWNIQWSDSTPHHDLL--RNMKRF 181
                   .||      :||          .::.........|...:|:|.|..:.||  .|....
  Rat   413 -------KVCQAYLGQLEH----------EDIDLSDASAEALSEEEWNDLTQQYYLLVHGNASIT 460

  Fly   182 QQINHFPGMVEICRKDLLSR--NLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYANKHKRTFILK 244
            ...::|..    |:. |||:  ::|             |:|.:            :..:..:|:|
  Rat   461 DSRSYFAQ----CQA-LLSKISSVN-------------PQTEI------------DGIRNIWIIK 495

  Fly   245 PYSAGQGRGI-----------WITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVD 298
            |.:..:||.|           .:.||.:|. |..|.:.|.|||.|:||...|||:|.:.|||..:
  Rat   496 PAAKSRGRDIVCMDRVENILDLVATDSQTT-KDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWN 559

  Fly   299 PLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNK 363
            ||.|:.|.|...||:||::......::    :||.|..:.||     :.|..|...  .|...|.
  Rat   560 PLTIWFYKESYLRFSTQRFSLDKLDSA----IHLCNNSIQRR-----LKNDKERSP--LLPCHNM 613

  Fly   364 WLVDHNYDV------GEFWASVDDAIIKTLISAWPTLKHNY-NVCFPKHDKIQA---SFQLLGFD 418
            |......:.      |..|.|:          .:|::|... |......|.::|   ||:|.|.|
  Rat   614 WTSTRFQEYLQKRGRGGTWGSI----------IYPSMKRAVTNAMRVAQDHVEARKNSFELYGAD 668

  Fly   419 ILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNMLSTALVDK-------EQIIRDDRT 476
            .::....||:::|:|.:|::.....|..::...:..||:.::....:|:       |.:.|....
  Rat   669 FILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVVVDRKLDRNCDIGNFELLWRQPAV 733

  Fly   477 E----HRARL-LRNIYNKKAAAQMPGYSSPIREVGGHD--------VRQACSIGALTQQIAWEES 528
            |    :.:.| :..|..|||..|||    ||..:|..|        .|.|..:         .|:
  Rat   734 ELPPFNGSDLCVEGISVKKAKKQMP----PIANLGFSDSLLDAPTKARSARPL---------PET 785

  Fly   529 HLGNYRRIMPP---RDSSKV--NYYCKFYEQNKQPMFADTVASRRREQLNLQAIQKHQRERQQDL 588
            .:|..|..:.|   |:.:||  |.:       ..|:.|..|..:.:.....            |:
  Rat   786 VIGPSRMTVRPDWKREEAKVLSNTW-------SAPVMAAEVRGQAKPTYAF------------DV 831

  Fly   589 IQQQQIHTQAQN------RMGKHVRWPGDLVQGEQVNPVILQSRRRREEAEAYAKKHRALIAREI 647
            ...|.:.::|..      :.|||          .:||.:..|              :.||:.:.:
  Rat   832 NNYQHVDSKAYKSTFTKVQSGKH----------SEVNLISAQ--------------YPALVLQNM 872

  Fly   648 QR 649
            ||
  Rat   873 QR 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	75/319 (24%)
Ttll8	XP_056840443.1	TTL	<489..711	CDD:397308	65/243 (27%)