Protein Alignment TTLL6A and Ttll7

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_063138994.1
• Gene: Ttll7 / 310982
• RGDID: 1566117
• Length: 900
• Species: Rattus norvegicus
• Alignment Length: 774
• Identity: 228/774 - (29%)
• Similarity: 366/774 - (47%)
• Gaps: 118/774 - (15%)

  Fly   135 VEHTRFQLVAKVTRNMGFQHVP-EHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEICRKDL 198
            |..|:|::|..|...|||...| |....|:.|.|:....:.:.:::.:|:|||||||.||||||.
  Rat    59 VAGTKFEIVRLVIDEMGFIKTPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDF 123

  Fly   199 LSRNLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYANKHK-----RTFILKPYSAGQGRGIWITT 258
            |:||:.:|:|..|.||...|:||:.|::......|..:.|     :|||:||.:...|.||.:..
  Rat   124 LARNMTKMIKSRPMDYTFVPRTWIFPSEYTQFQNYVKELKKKRKQKTFIIKPANGAMGHGISLIR 188

  Fly   259 DLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTG 323
            :...:..::.||.|.|||:|.|::|||||||:|.||||.|||:||:|::||.|..|:||:||...
  Rat   189 NGDKIPSQDHLIVQEYIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNES 253

  Fly   324 NSHNVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLI 388
            |...::||||||.:|:.|.::......:.||||.:..|.::|..:.:||.:||:.:.:.::||||
  Rat   254 NLTQLYMHLTNYSVNKHNERFERNETEDKGSKRSIKWFTEFLQANQHDVTKFWSDISELVVKTLI 318

  Fly   389 SAWPTLKHNYNVCFPKHDKIQAS--FQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRP 451
            .|.|.:.|.|.:|.|.......|  |::||||||:|.||||::||:|..||...|:.:|.:|||.
  Rat   319 VAEPHVLHAYRMCRPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRG 383

  Fly   452 LIRDTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGY-SSPIREV--GGHDVRQA 513
            ::.:.|.:|:....||.               :|:..:||.||...| .:|||.:  |..|..|.
  Rat   384 VLLNALKLLNIRTSDKR---------------KNLAKQKAEAQRRLYGQNPIRRLSPGSSDWEQQ 433

  Fly   514 C------------SIGALTQQIAWEE---SHLGNYRRIMPPRDSSKVNYYCKFYEQNKQPMFADT 563
            .            .:..:.:||:.||   .|:||||||.||.|.:.:..|........|...:..
  Rat   434 RHQLERRKEELKERLLQVRKQISQEEHENRHMGNYRRIYPPEDKTLLEKYEGLLAVAFQTFLSGR 498

  Fly   564 VASRRREQLNLQAIQKHQRERQQDLIQQQQIHTQAQNRMGK--HVRWPGDLV------------- 613
            ..|..||..|  .::|.:.|...||::|.:|  ..:..|||  .||.|..|.
  Rat   499 ATSFHREMNN--PLKKMREEDLLDLLEQCEI--DDEKLMGKTTRVRGPKPLYCMPECAEVMKMQK 559

  Fly   614 -----------QGEQVNPVILQSRR----RREEAEAYAKKHRALIAREIQRQKEQLLAPTCAKER 663
                       .|...|..:.:|.:    :|.:...|:.||..|. ::....:..:..|......
  Rat   560 YYGSSDSSYDSSGSSSNSDLDESDKELCQKRLDQVPYSFKHSKLF-QQSNSMRRSVSCPRSISAH 623

  Fly   664 LGIWQSVRREKRSQFSP-KRGSSITKAYRRKQQRNLSLRARQQRMIEMEAQRDAKFLEQHAQKQR 727
            |.....||.....|..| .|.:|.::::        ||......|..:....||.........:.
  Rat   624 LPSRGDVRPFSSQQVIPLARPTSASRSH--------SLNRASSYMRHLPHSHDASSASNALVNES 680

  Fly   728 LEGGRKTGQSESPNLLSKITAKSKTSLK-KKMKPKGKPELKKETLQEG--NHCQMTKSKVELTPG 789
            |. ..||.:.|     ..:|:::...|| .:::..||.:.:.|.|.|.  ::.:..|:||
  Rat   681 LR-QLKTKEQE-----DDLTSQTLFVLKDMRIRFPGKSDAESELLIEDIMDNWKHYKTKV----- 734

  Fly   790 SKARAFANWTARTINEAETDQLLS-------------WRKERANQLNETRLRELIFSKM 835
                  |::....::..:..::|.             ||...|.:|:..|:...:|:::
  Rat   735 ------ASYWLIKLDSVKQRKVLDIVKSSIRTVLPRIWRVPDAEELSLYRIFNRVFNRL 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	126/296 (43%)
Ttll7	XP_063138994.1	None