Protein Alignment TTLL6A and Ttll6

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_063126212.1
• Gene: Ttll6 / 287646
• RGDID: 1311922
• Length: 940
• Species: Rattus norvegicus
• Alignment Length: 806
• Identity: 263/806 - (32%)
• Similarity: 396/806 - (49%)
• Gaps: 172/806 - (21%)

  Fly   129 LRLSVCVEHTRFQLVAKVTRNMGFQHVPEHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEI 193
            :.||.|    |:..|.:..:..|.:...::..|.:.|:|.:...:.:..||.:|:|||||||.||
  Rat    63 INLSNC----RYDSVRRAAQQYGLREAGDNDDWTLYWTDYSVSLERVMEMKSYQKINHFPGMSEI 123

  Fly   194 CRKDLLSRNLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIYANKHK-RTFILKPYSAGQGRGIWIT 257
            ||||||:||::||||:||.|:..||:||.:|.|..|:..|:...| :|:|.||.|..|||||:||
  Rat   124 CRKDLLARNMSRMLKLFPKDFHFFPRTWCLPADWGDLQTYSRTRKNKTYICKPDSGCQGRGIFIT 188

  Fly   258 TDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTT 322
            ..::.:...|.:|||.||.:|.:|||:|||||||.||||.||||:||||||||||||..|..|.|
  Rat   189 RSVKEIKPGEDMICQLYISKPFIIDGFKFDLRVYVLVTSCDPLRVFVYNEGLARFATTSYSHPNT 253

  Fly   323 GNSHNVFMHLTNYCLNRRNSQYMVGNGPEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTL 387
            .|...:.||||||.:|:.:|.::  ....:|||||||.||.::..|.|||.:.|.:::|.|||||
  Rat   254 ENLDEICMHLTNYSINKHSSNFI--QDAHSGSKRKLSTFNSYMKTHGYDVEQIWRAIEDVIIKTL 316

  Fly   388 ISAWPTLKHNYNVCFPKHDKIQASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPL 452
            |||.|.:||||:.|||.|....|.|::||||||:|.||||::|||||:||.|.|..:|.|||..|
  Rat   317 ISAHPVIKHNYHTCFPSHTLNSACFEILGFDILLDRKLKPWLLEVNHSPSFSTDSKLDKEVKDSL 381

  Fly   453 IRDTLNMLSTALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGYSSPIREVGGHD-VRQACSI 516
            :.|.|.:::....||::::.::|  .|.|.|:         |.|.....:.||.|.. ||
  Rat   382 LYDALVLVNLGSCDKKKVLEEER--QRGRFLQ---------QCPNREIRMEEVKGFQAVR----- 430

  Fly   517 GALTQQIAWEESHLGNYRRIMPPRDSSKVNYYCKFYEQNKQPMFADTVASRRREQLNLQAIQKHQ 581
              |.:...:|:.:.|.:|.|.|.::..|   |.||::.|.. :|.:|||||.||        .:.
  Rat   431 --LQKTEEYEKKNCGGFRLIYPGQNLEK---YEKFFQDNSS-LFQNTVASRARE--------LYA 481

  Fly   582 RERQQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNPVILQSRRRRE-EAEAYAKKHRALIAR 645
            |:..|:|.|:||                         |...|:..|:.| :.|:..::.|..|.|
  Rat   482 RQLIQELRQKQQ-------------------------NKFFLKKERKEEMQGESAGEQARDKIVR 521

  Fly   646 EIQRQKEQLLAPTCAKERLGIWQSVRREKRSQFSPKRGSSITKAYRRKQQRNLSLRARQQ----R 706
             :||.::|   |.|              |.:...||:.........|.....|::|..::    |
  Rat   522 -LQRPRQQ---PKC--------------KPATCPPKQSFHPVNLGSRASSLLLNIRGLKKSETAR 568

  Fly   707 MIEMEAQRDAK------------------------------FLEQHAQKQRLEGGRKTGQSESPN 741
            .::   |:|:|                              .||.|....::   ::...:.|.|
  Rat   569 SLD---QKDSKNEVVLIPCKPVSARNYSSVPDLRSSNPSYSELEFHMANSKV---KEVKSAFSVN 627

  Fly   742 LLSKITAKSKTSLKKKMK-----------------PKGKPELK-------------KETLQE--- 773
            ::|.........|:..|:                 |..:|..:             |:||.:
  Rat   628 IVSSAQVLGPLGLRAAMRVLRVEPGLSFMADPSLQPTAEPSEQLSKVFGYCSQSQVKKTLSDAEF 692

  Fly   774 GNHCQMTK--SKVELTPGSKA------RAFANWTART--INEAETDQLLSWRKERANQLN----E 824
            .:|...:|  :.||.:|.:.|      .:.|:..:.|  .:..|:..:.|:..::....|    |
  Rat   693 ADHLSTSKPITPVETSPDATAPISTSLESLASSLSTTPECSSPESIHMASYNHKQQKASNKPTQE 757

  Fly   825 TRLRELIFSKMYE---NGHLTKNDIK 847
            .:.:.|:|||..:   |....|||||
  Rat   758 KKSKPLMFSKSRQLDLNCTSMKNDIK 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	158/290 (54%)
Ttll6	XP_063126212.1	None