Protein Alignment TTLL6A and ttll-4

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: NP_001022985.1
• Gene: ttll-4 / 176427
• WormBaseID: WBGene00014232
• Length: 601
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 152/599 - (25%)
• Similarity: 265/599 - (44%)
• Gaps: 154/599 - (25%)

  Fly    74 NEDHIMVVTQDNTQQQRDK--------------------PLLTASQLDSICYDVIKEPPMQFHVN 118
            |:..|:.:::..|:.:|.|                    |.|.:||...:      .|.::|:..
 Worm    68 NDIEIVGLSKTTTKVKRSKKVLSCPIVSSSTKKENGNAAPFLKSSQFTDV------PPTIRFYTK 126

  Fly   119 GTDIVPSIRGL--RLSVCVEHTRFQLVAKVTRNMGFQHVPEHRLWNI----------QWSDSTPH 171
            ||.:....|.:  ||:.| .::...:|.:.|.......|.:..|:.:          |:....||
 Worm   127 GTKVTKPARKIQARLTWC-HNSLLPIVMRQTLAASHFTVVDESLFYVGYWGRHLKSAQYRALQPH 190

  Fly   172 HDLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMFPGDYRIFPKTWLMPTDAYDVAIY--- 233
                      |::|||||...|.|||.|..::.:..:.|.|::.|.|.|:::|||..::..|
 Worm   191 ----------QKVNHFPGAFHIGRKDRLWMHIRKQQERFEGEFDIMPFTYILPTDRQELLKYLET 245

  Fly   234 -ANKHKRTFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYTLVTSV 297
             |::|   .|:||.::.:|.||.:|...:.......|:.|.||||||.|:..|||||:|..|.:.
 Worm   246 DASRH---VIVKPPASARGTGISVTRKPKDFPTTATLVAQHYIERPLTINRAKFDLRLYAYVPTF 307

  Fly   298 DPLRIFVYNEGLARFATQKYVPPTTGNSHNV------FMHLTNYCLNRRNSQYMVGNGPEAGSKR 356
            :|||:::|::||.|||:..|       ||:|      :||||||.:|:......|.|.|
 Worm   308 EPLRVYIYDQGLVRFASVPY-------SHSVSTISNKYMHLTNYSINKLAEADGVANKP------ 359

  Fly   357 KLSAFNKWLVDH--------NYDVGEFWASVDDAIIKTLISAWPTLKHNYN-------VCFPKHD 406
                ..||.:.|        ..|..:....:::.|||..||....::.:.:       :|
 Worm   360 ----VPKWTLHHLWEHFDEMGVDREKIQREIEEVIIKAFISTEKPIREHMSRFLEQEFIC----- 415

  Fly   407 KIQASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNM-----------L 460
                 ::|.|.||::|...||::||||.:|||.:...:|:.||.||.:|.||:           |
 Worm   416 -----YELFGIDIILDEDYKPWLLEVNISPSLHSGTPLDVSVKAPLAKDVLNLAGVYVPPSFDKL 475

  Fly   461 STALVDKEQIIRDDRTEHRARLLRNIYNKKAAAQMPGYSSPIREVGGHDVRQACSIGALTQQ--- 522
            |.|  |.....|:.| ::|.:|:      |.|:.:..|...:..:.....::      ||.:
 Worm   476 SDA--DYSTRPRNGR-KNREQLI------KEASWVAAYKDQLGVIDNRIFKR------LTPEDTR 525

  Fly   523 --IAWEE--SHLGNYRRIMPPRDSSKVNYYCKFYEQN-------KQPMFAD----TVASRRREQL 572
              :.:|:  ..:|:::.:.|   ::..::|.|::.:.       :|...|.    ::...|.|||
 Worm   526 ALVEFEDELERIGDFKLVFP---TAHTSHYQKYFAETIYMNILLQQWQIAQEDDRSIGINRLEQL 587

  Fly   573 NLQAIQKHQRERQQ 586
               ..|||.:..|:
 Worm   588 ---CRQKHMQSDQE 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	104/325 (32%)
ttll-4	NP_001022985.1	TTL	189..474	CDD:397308	102/324 (31%)