Protein Alignment TTLL6A and TTLL5

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_313563.5
• Gene: TTLL5 / 1274440
• VectorBaseID: AGAMI1_014267
• Length: 1115
• Species: Anopheles gambiae
• Alignment Length: 707
• Identity: 194/707 - (27%)
• Similarity: 306/707 - (43%)
• Gaps: 127/707 - (17%)

  Fly    34 QKQEIYNRESVYVLSNKSRGKRRSGRENNQPTWRRRGGGVNEDHIMVVT------------QDNT 86
            :|:::.:..|...|||.|....:.|..:...|  ......:|..:.:..            ::|.
Mosquito   267 KKRQLESSSSSSSLSNASMSSVKGGSGDEIDT--EMSTSKSEPSLAMAALDKKLAAQRKQKEENK 329

  Fly    87 QQQRDKPLLT---ASQLDSICYDVIKEPPMQFHVNGTDIVPSIRGLRLSVCVEHTRFQLVAKVTR 148
            :.|:..||.|   |:|| :|||..|                            :|..:|:.|:..
Mosquito   330 ENQQTAPLKTEMPAAQL-NICYKFI----------------------------NTETRLLRKILN 365

  Fly   149 NMGF-QHVPEHRLWNIQWSDSTPHHDLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRM--LKMF 210
            ..|. :..||...:|:.|:......|:|||:..:|::||||...|:.|||.|.:|:.||  |:.:
Mosquito   366 AHGMGESGPECNDFNLLWTGIHLKPDILRNLAPYQRVNHFPRSYELTRKDRLYKNIERMQHLRGY 430

  Fly   211 PGDYRIFPKTWLMPTDAYDVAIYANKHKRTFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYI 275
            . .:.|.|:::|:|.|..::....||.:..:|:||.::.:||||:|......:...|:::...||
Mosquito   431 K-HFDIVPQSFLLPQDYKELIAAHNKCRGPWIVKPVASSRGRGIFIVNSPDQISSFEQVVVAKYI 494

  Fly   276 ERPLLIDGYKFDLRVYTLVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRR 340
            ..||.|||:|.|:|:|..|||.|||.|::|.|||.|.||.|| ..|..|..|..|||.||.:|:.
Mosquito   495 SDPLCIDGHKCDIRIYVAVTSFDPLIIYIYEEGLVRLATVKY-DRTAENLWNPCMHLCNYSINKY 558

  Fly   341 NSQYMVGNG---PEAGSKRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISAWPTLKHNYNVC- 401
            ::.|:..:.   .:.|.|..|||..:.|.....:..:...:::|.|||.:.|....:   .:.|
Mosquito   559 HTDYIKSSNAGEEDVGHKWTLSALLRHLRSQGCNTEQLMLAIEDLIIKAIFSCTQPI---VSACR 620

  Fly   402 -FPKHDKIQASFQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNM------ 459
             |..|  |...|:|.|||||:|..|||::||||.:|||..|..:|.:||..::.|.|.|
Mosquito   621 MFVPH--IGNCFELYGFDILIDDMLKPWLLEVNLSPSLGCDTPLDTKVKASMLTDLLTMVGIPAI 683

  Fly   460 --LSTALVD-KEQIIRDDRTEHR----ARLLRNIYNKKAAAQMPGYSSPIREVGGHDVRQACSIG 517
              |..|..| |.|.||:..|.:|    |..:.....:|..|...|.....:..|....:...::.
Mosquito   684 SPLQKACYDSKGQKIRNLTTPYRRVNSADFVHTTSGRKEGAGTGGSGQQQQGKGDGGGKLQTTLS 748

  Fly   518 ALTQQ----IAWEESHL---GNYRRIMPPRD---------------------SSKVNYYCKFYEQ 554
            |||.:    :.:..|..   |.:.||.|..|                     ||....|......
Mosquito   749 ALTAEELKIVRFARSQYERRGGFVRIFPTSDSMNRYGSLLDPITGIPTSAITSSSSGTYLMIIPH 813

  Fly   555 NKQPMFADTVASRRREQLN--LQAIQKHQRERQQDL-IQQQQIHTQAQ-----NRMGKHVRWPGD 611
            |...|....:.....|..|  :..|||::|..:..| |.....|...:     .|:...||   .
Mosquito   814 NYNQMLHSQLFPPGSETENRIVHRIQKYERALESSLPITIGPKHAAPKCVDEAKRLRLQVR---K 875

  Fly   612 LVQ-GEQVNPVILQSRR----------RREEAEAYAKKHRALIAREIQRQKEQLLAP 657
            |:: |.:::  |||:||          :|..:|. ...|..||.:.:.|....:..|
Mosquito   876 LIENGHEMS--ILQARRAFGFYLEYILKRLSSEP-KHSHEELIMKFLYRVGAHMKTP 929

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	112/305 (37%)
TTLL5	XP_313563.5	None