Protein Alignment TTLL6A and ttll5

DIOPT Version :10

• Sequence 1: NP_611433.3
• Gene: TTLL6A / 37253
• FlyBaseID: FBgn0034459
• Length: 867
• Species: Drosophila melanogaster
• Sequence 2: XP_012823512.2
• Gene: ttll5 / 100158545
• XenbaseID: XB-GENE-5889203
• Length: 1128
• Species: Xenopus tropicalis
• Alignment Length: 799
• Identity: 196/799 - (24%)
• Similarity: 345/799 - (43%)
• Gaps: 175/799 - (21%)

  Fly   109 KEPPMQFHVNGT---DIVPSIRGL----RLSVCVEHTRFQLVAKVTRNMGFQHV-PEHRLWNIQW 165
            |.|.:.||....   ::  |:|.:    :||..:..|..:||..:....|||.| .....:||.|
 Frog    36 KVPIVMFHAEAVLHKNL--SLRAVGERYKLSYKIVRTDSRLVRSILSAHGFQEVNANSNDFNIMW 98

  Fly   166 SDS--TPHHDLLRNMKRFQQINHFPGMVEICRKDLLSRNLNRMLKMFP-GDYRIFPKTWLMPTDA 227
            :.|  .||  ::|::..||::||||...|:.|||.|.:|:.||.:... .::.:.|:|:|:|.:.
 Frog    99 TGSHVKPH--IMRSLTNFQKVNHFPRSYELTRKDRLYKNVQRMQQSHGFKNFHLLPQTYLLPAEY 161

  Fly   228 YDVAIYANKHKRTFILKPYSAGQGRGIWITTDLRTVGKREKLICQTYIERPLLIDGYKFDLRVYT 292
            .|......|.:..:|:||.::.:|||:::......:...:.::...||..||||||:|||:|:|.
 Frog   162 QDFCTAFAKDRGPWIVKPVASSRGRGVYLINSPSLISMEDNILVSRYIGNPLLIDGFKFDVRLYV 226

  Fly   293 LVTSVDPLRIFVYNEGLARFATQKYVPPTTGNSHNVFMHLTNYCLNRRNSQYMVGNGPEA---GS 354
            |:||.|||.|::|.|||.||||.|| .....|..|.|||||||.:|:::..|:..:.|:.   |:
 Frog   227 LITSYDPLVIYLYEEGLTRFATAKY-DRAAKNIKNQFMHLTNYSVNKKSGDYVSCDDPDVEDYGN 290

  Fly   355 KRKLSAFNKWLVDHNYDVGEFWASVDDAIIKTLISA--------WPTLKHNYNVCFPKHDKIQAS 411
            |..:||..::|.....|.....:.|:|.||||::||        ...:.|..| |
 Frog   291 KWSMSAMLRYLKQDGKDTAALMSQVEDLIIKTIVSAELPIASACKSLITHRGN-C---------- 344

  Fly   412 FQLLGFDILVDWKLKPYILEVNHTPSLSADESVDMEVKRPLIRDTLNMLSTALVDKEQIIRDDRT 476
            |:|.|||:|:|..|||::||||.:|||:.|..:|::||..:|.|...::.....|.:|
 Frog   345 FELYGFDVLIDGNLKPWLLEVNLSPSLACDAPLDLKVKASMISDMFTLVGVECQDPQQ------- 402

  Fly   477 EHRARLLRNIYNKKAAAQMPGYSSPIREVGGHDV--------------RQACSIG------ALTQ 521
             ...|...::|:|:...     |:..|.:..:|:              |.:|.:|      .:.:
 Frog   403 -RFGRASSSLYDKRTQK-----STHQRPLSANDIDTGLQGGNREKAVRRTSCLLGLSIEELKILR 461

  Fly   522 QIAWEESHLGNYRRIMPPRDS-----------SKVNY---------------YCKFYEQNKQPMF 560
            ::..|....|.:.||.|..::           :.:||               :|   |:|..|..
 Frog   462 RVQDEYERRGGFVRIFPRHNTWQLYGSFLEYKTSLNYMLVTHLFPNRAAGNDHC---EKNWDPRM 523

  Fly   561 ADTVASRRREQLNLQAIQKHQRERQQDLIQQQQIHTQAQNRMGKHVRWPGDLVQGEQVNPVILQS 625
            ......|:...|:|:..:.....|:..|....|.....|:.                      :.
 Frog   524 HAAFYERKLVSLHLRRARHRGLTRKTGLSHAPQCSDHEQSS----------------------KE 566

  Fly   626 RRRREEAEAYAKKHRALIAREIQRQKEQLLAPTCAK-----ERLGIWQSVRREKRSQFSPKRGSS 685
            :..:||.|...:.|      |::..:|::.:|..:|     .|:.:...:|  |.:..|..:..:
 Frog   567 QEEQEEEEELDENH------ELEVVQEKVSSPDSSKIIIPPPRISLMDILR--KGADLSKVQARN 623

  Fly   686 ITKAYRRKQQRNLSLRARQQRMIEMEAQRDAKFLEQHAQKQRLEGGRKTGQSESPNLLSKITAKS 750
            ....|.::.|..|......:|:             |..:::::|...:..|..:.||
 Frog   624 AFSCYLQRVQNRLQTERNPERV-------------QPKEEEQIELVMRFLQRGAANL-------- 667

  Fly   751 KTSLKKKMKPKGKPELKKETL----------------QEGNHCQMTKSKVELTPGSKARAFANWT 799
            |.||...:..:..|.|::..|                |:..:.:.|:|..|.  |.....|..:.
 Frog   668 KRSLPLNLPGQSVPYLERRHLLAKLLGDFVALYNQETQQMQNSEETQSNEEC--GVNPDDFEAFV 730

  Fly   800 ARTINEAETDQLLSWRKER 818
            | ..:|.|.:::|::..::
 Frog   731 A-DASENELEEVLTFYTQK 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL6A	NP_611433.3	TTL	181..471	CDD:397308	110/301 (37%)
ttll5	XP_012823512.2	TTL	113..390	CDD:397308	108/288 (38%)