DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir56d and Ir94d

DIOPT Version :9

Sequence 1:	NP_611432.1	Gene:	Ir56d / 37252	FlyBaseID:	FBgn0034458	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	624	Identity:	139/624 - (22%)
Similarity:	251/624 - (40%)	Gaps:	126/624 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 EMFYRITQLYHFKNFIFYISERLDLNNKDSQEFFHNFW--TYFPMAPNLIITREHHLGIPMMQFI 96
            :.||.  .|.|..|....|...|.|.|      |...|  ..:.:..:::..:||  .......:
  Fly    19 DSFYH--SLIHHLNRELKIEYVLLLGN------FDTTWLDILWQLPVSVLQIKEH--SRETYSLL 73

  Fly    97 STPS---LVMVFTTGKDDPIMELASHNQQGIHWLKTIFVLFPSLQSRDFETNPESLAQFTAEIKD 158
            ..||   |.:.|.....:.|:|:...|.:.::....:.|:..|                |..:..
  Fly    74 ENPSHNVLTIAFVNDSPEDILEILYRNLRMLNTQPVLLVIRKS----------------TIRVNS 122

  Fly   159 VYDWVWRKQFINTFLITIKDN------VFILDPYPTPSIV-----NKTGVWQAEEFFHKYAKNMK 212
            :.:|.|..|.:.  ::.|..:      |:..:|:|....:     |.|.:      |.|..:|:.
  Fly   123 LLEWCWHHQLLK--VVAIAQDFMESLIVYSYNPFPVLQFIERRLDNSTVI------FEKRLENLH 179

  Fly   213 GYLVRTPILYDMPR--VFKSDRPTNRYEKNFIHGTSGNLFLGFLEFVNATLM-----DTSANVTA 270
            ||.|...:....||  |::     :...|....|..||....|.:..|..|:     |.||...|
  Fly   180 GYEVPIALGGSSPRLIVYR-----DLEGKLIFSGPVGNFMKSFEQRYNCRLVQPYPFDESAISPA 239

  Fly   271 DYLNMTNLLDLVSQGVYETLIHS-FTEITTKFVVSYSYPIGINDCCIMVPYRNQSPADQYMHEAL 334
                 .:|:..|..|..:..:.: :.::.   ...|||||.:...|:|:|...:.|     |..|
  Fly   240 -----RDLIASVQNGSVQIALGAIYPQVP---YTGYSYPIELMSWCLMMPVPEEVP-----HSQL 291

  Fly   335 QENVW------------VLISLFTLYITVAI--YLCSPLRPRDLSAAFLQSICTLTYSVPTF--I 383
            ...|:            ||||| ||.:.:.:  |..|      .|..||...|.......:|  :
  Fly   292 YSMVFSPMAFGITIVAMVLISL-TLSMALRLHGYRVS------FSEYFLHDSCLRGVLSQSFYEV 349

  Fly   384 IRTPTLRMRYLYILLAIWGIVTSNLYISRMTSYFTTAPPVRQINTVQDVVEANLRIKMLAIEYER 448
            :|.|.| ::.:|:::.:.|::.::.|.|..:::.|:||...|:.:.:.:..:|::|.:...|||.
  Fly   350 LRAPAL-IKAMYLVICLLGLLITSWYNSYFSTFVTSAPRFPQLTSYESIRHSNIKIVIWKPEYEM 413

  Fly   449 M---AKSPLQYPESYLNQVDLVDKHMLDLHRDPFNTSFGYTVSSDRWRFLNLQQLHLRKPIFRL- 509
            :   :::..:|...:..|.|.  |..|.| ||.|:|.:||.:..::|..:..||.....|:|.|
  Fly   414 LLFFSENMEKYSSIFQLQEDY--KEFLHL-RDSFDTRYGYMMPMEKWSLMKEQQRVFSSPLFSLQ 475

  Fly   510 TEICEGPFYH----VFPLHKDSHMRSVMTEYIMIAQQAGLMNHWERETFWEAVHLHRIHVHLFDD 570
            .::|   .:|    |||:.|:|..:......|:.....||::.|...:|.|.:...::.:   :|
  Fly   476 DDLC---VFHTVPIVFPMVKNSIFKEPFDRLILDVTATGLLSRWRDMSFTEMIKAGQLGL---ED 534

  Fly   571 -----EPMALSLDFFSSLLR--TWTLGLILAGLAFAAEM 602
                 |..|:.:.....:.|  .|.||  ||.:.|..|:
  Fly   535 RGHPKEFRAMKVGDLIQIWRFVGWMLG--LATIVFLLEL 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir56d	NP_611432.1	ATPase-IIIA_H	<312..422	CDD:273731	30/125 (24%)
Ir94d	NP_001138099.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010