DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir56d and Ir94e

DIOPT Version :9

Sequence 1:	NP_611432.1	Gene:	Ir56d / 37252	FlyBaseID:	FBgn0034458	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_001097885.2	Gene:	Ir94e / 42765	FlyBaseID:	FBgn0259194	Length:	611	Species:	Drosophila melanogaster

Alignment Length:	665	Identity:	145/665 - (21%)
Similarity:	262/665 - (39%)	Gaps:	123/665 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NGSDNITLLNNMFVLEMFYRITQLYHFKNFIFYISERLDLNNKDSQEFFHNFWTYFPMAPNLIIT 83
            :|:..|.||..: .||:.:....|  .||..|.:|:::              |....:..:::
  Fly    18 SGATVIELLGTL-KLELDFEYVLL--MKNRNFSLSDQV--------------WNGTSLTKDVM-- 63

  Fly    84 REHHLGIPMMQF-----------ISTPSLVMVFTTGKD-DPIMELASHNQQGIHWLKTIFVLF-- 134
              ..:.:|::||           ||...:.:.|.:..: |....|.:.....:..:.|..|:|
  Fly    64 --DEVQVPVLQFNENVSYFLHNSISRRLVTLGFMSDANLDEHRGLLTALVANLRHMTTSRVIFLV 126

  Fly   135 PSLQSRDFETNPESLAQFTAEIKDVYDWVWRKQFINTFLI----TIKDNVFILDPYPTPSI---V 192
            .|..|.||             :.:::...|||:.:|..:|    ......:....:|...|   :
  Fly   127 QSKASTDF-------------LYELFRNCWRKKLLNVIVIFQDFETTSTFYSYSNFPILQIEERI 178

  Fly   193 NKTGVWQAEEFFHKYAKNMKGYLVRTPILYDMPRVFKSDRP---TNRYEK-NFIH-GTSGNLFLG 252
            .:|.: |....|....:|:.|        |:||.:.....|   ..|.:| |.:: ||.|:....
  Fly   179 YETSL-QTLPIFPDRLRNLHG--------YEMPVILGGTAPRMIAYRNKKGNVVYDGTVGHFMTA 234

  Fly   253 FLEFVNATLMDTSANVTADYLNMTNLLDLV-SQGVYETLIHSFTEITTKFV------VSYSYPIG 310
            |.:..|...:..        |...|.||.. |......:.:...||:....      ..:|||..
  Fly   235 FQQKYNVKFVQP--------LQAKNPLDFAPSMQTVGAVRNETVEISISLTFPTIPPFGFSYPYE 291

  Fly   311 INDCCIMVPYRNQSPADQYMHEALQENVWVLISLFTLYITVAIYLCSPLR----PRDLSAAFLQS 371
            ..:.|:|:|.....|..:| :..:.|....|::|.|| :.::..|.|.|.    ..::|...|..
  Fly   292 QMNWCVMLPVEADVPPFEY-YTRVFELAAFLLTLGTL-VLISCLLASALSLHGYATNISEFLLHD 354

  Fly   372 ICTLTYSVPTF--IIRTPTLRMRYLYILLAIWGIVTSNLYISRMTSYFTTAPPVRQINTVQDVVE 434
            .|.......:|  :.|.||| :|.:|:.:.:.||:.:..|.|..:||.|:||......|..|::.
  Fly   355 SCLRGVLGQSFVEVFRAPTL-VRGIYLEICVLGILITAWYNSYFSSYVTSAPKQPPFRTYDDILA 418

  Fly   435 ANLRIKMLAIEYERMAKSPLQ---YPESYLNQVDLVDKHMLDLHRDPFNTSFGYTVSSDRWRFLN 496
            :.|::.....||..:....|:   |...:|.:.|.  ...|.| ||..:|.:||.::::||..:|
  Fly   419 SKLKVVAWKPEYAELVGRLLEFRKYETMFLVEPDF--NRYLAL-RDTLDTRYGYMITTNRWVLIN 480

  Fly   497 LQQLHLRKPIF-RLTEICEGPFYH----VFPLHKDSHMRSVMTEYIMIAQQAGLMNHWERETFWE 556
            .||....:|:| :..:.|   |::    .||||::|.....:.:.||...:.||..||....|.|
  Fly   481 EQQKVFSRPLFQKRDDFC---FFNNIPFGFPLHENSVFMEPVQKLIMELAETGLYYHWITTGFSE 542

  Fly   557 AVHLHRIHVHLFDD-----EPMALSLDFFSSLLRTWTLGLILAGLAFAAEMKWHEHVTFKRRPVI 616
            .:....:|   |.|     |..|:.:.....:...:...::|:.|.:..|   :...|.|.:.:.
  Fly   543 LIDAGEMH---FVDLSPHREFRAMQIQDLQYVWYGYAFMVVLSSLVWLLE---NLAYTVKSKTIF 601

  Fly   617 RITRKPRSFLRRFMK 631
                 |..|::|..|
  Fly   602 -----PTHFMQRNKK 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir56d	NP_611432.1	ATPase-IIIA_H	<312..422	CDD:273731	31/115 (27%)
Ir94e	NP_001097885.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010