DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir56d and Ir52d

DIOPT Version :9

Sequence 1:	NP_611432.1	Gene:	Ir56d / 37252	FlyBaseID:	FBgn0034458	Length:	632	Species:	Drosophila melanogaster
Sequence 2:	NP_611042.2	Gene:	Ir52d / 36716	FlyBaseID:	FBgn0050464	Length:	594	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	134/558 - (24%)
Similarity:	227/558 - (40%)	Gaps:	75/558 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 LGIPMMQFISTPSLVMVFTTGKDDPIMELASHNQQGIHWLKTIFVLFPSLQSRDFETNPESLA-- 150
            |.:...||.:|   ::::  |:|.....|:...|     :.||.|   |..|..||.|..|||
  Fly    38 LRLQQEQFFNT---LLIY--GEDCAFSSLSRRLQ-----VPTILV---SSGSTSFEWNYSSLALI 89

  Fly   151 ---QFTAEIKDVYDWVWRKQFINTFLITIKDNV---FILDPYPTP-----SIVN----KTGVWQA 200
               :|.||.::.|..: :|..:|..||.:..|:   .:.|.|...     ::||    :.|:..|
  Fly    90 LTCEFKAEREENYQTL-KKLQMNRRLILLNGNIKPDSVCDFYSKKDQYNIAMVNNNFHQVGIIYA 153

  Fly   201 EEFFHK--YAK---------------NMKGYLVRTPILYDMPRVFKSDRPTNRYEKNFIHGTSGN 248
            ...|.:  |.|               ||:|.|:::.....:|.......|....||:.  |...|
  Fly   154 CRLFQERNYEKVYLSEGNPIYVDQFRNMQGALLKSITFNLIPGSMAYRDPKTGQEKHI--GYVAN 216

  Fly   249 LFLGFLEFVNATL-MDT---SANVTADYLNMTNLL--DLVSQGVYETLIHSFTEITTKFVVSYSY 307
            |...|:|.||||| |..   .|.....:.|:|...  |||..|:........|...|     .||
  Fly   217 LLNNFVEKVNATLDMQVKLHKAGKKTSFYNITKWASEDLVDIGMSYAAYFEMTNFDT-----ISY 276

  Fly   308 PIGINDCCIMVPYRNQSP-ADQYMHEALQENVWVLISLFTLYITVAIYLCS-PLRPRDLSAAFLQ 370
            |..:...|.|||..:..| ::.||.......:.|||::|.::..:..|:.. ..|...|....|.
  Fly   277 PYLMTSTCFMVPLPDMMPNSEIYMGIVDPPVLVVLIAIFCIFSVMLNYIKQRSWRSLSLVNVLLN 341

  Fly   371 SICTLTYSVPTF-IIRTPTLRMRYLYILLAIWGIVTSNLYISRMTSYFTTAPPV-RQINTVQDVV 433
            .||...:....| ..|....:::.:.:|:..:.::|:.:|.|.:.| |...||: .::.:..|:
  Fly   342 DICLRGFLAQPFPFPRQSNRKLKLISMLVCFFSVITTTMYTSYLQS-FMWGPPIDPKMCSFADL- 404

  Fly   434 EANLRIKMLAIEYERMAKSPLQYPESYLNQVDLVDKHMLDLHRDPFNTSFGYTVSSDRWRFLNLQ 498
             .|.|.|:....|:.....|......::...|  :...|:..||.|:.::.|.:|:..|.....|
  Fly   405 -ENSRYKLAIRRYDIEMLRPFNVSMDHVVVFD--ESSQLEYLRDSFDDNYMYPMSALSWSAFKEQ 466

  Fly   499 QLHLRKPIFRLTE-ICEGPF-YHVFPLHKDSHMRSVMTEYIMIAQQAGLMNHWERETFWEAVHLH 561
            |.....|:|..:| :|..|. :..||:.:....|.:..|:::...:.||..:|...:|.:.|.|.
  Fly   467 QKLFAFPLFYYSEKLCLKPISFFSFPIRRHLPYRDLFEEHMLQQNEFGLSTYWIDRSFSDMVRLK 531

  Fly   562 RIHVHLFDDEPMALSLDFFSSLLRTWTLGLILAGLAFA 599
            ...::  |..|..|. |:......:|..|:...||..:
  Fly   532 LATMN--DFSPPRLE-DYIEVSDLSWVFGMYFTGLGIS 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir56d	NP_611432.1	ATPase-IIIA_H	<312..422	CDD:273731	25/112 (22%)
Ir52d	NP_611042.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010