Protein Alignment Ir56d and GRIK3

DIOPT Version :9

• Sequence 1: NP_611432.1
• Gene: Ir56d / 37252
• FlyBaseID: FBgn0034458
• Length: 632
• Species: Drosophila melanogaster
• Sequence 2: NP_000822.2
• Gene: GRIK3 / 2899
• HGNCID: 4581
• Length: 919
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 60/325 - (18%)
• Similarity: 112/325 - (34%)
• Gaps: 112/325 - (34%)

  Fly   192 VNKTGVWQAEEFFH--KYAKNMKG----------YLVRTPILYDMPRVF-KSDRP---TNRYE-- 238
            :.|.|||...:..:  :.||. :|          .|:.|.:|.:...:| ||||.   .:|:|
Human   402 LEKVGVWSPADGLNITEVAKG-RGPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEGY 465

  Fly   239 -----KNFIHGTSGNLFLGFLEFVNAT--------------------LMDTSANVTADYLNMTNL 278
                 |...|      .|||...:...                    |:|..|::....|.:|::
Human   466 CIDLLKELAH------ILGFSYEIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHV 524

  Fly   279 LD--------LVSQGVYETLIHSFTEITTKFVVSYSYP-------------IGINDCCIMVPYRN 322
            .:        .::.||  ::::.....|...|.|:..|             :|::  |::.....
Human   525 REKAIDFSKPFMTLGV--SILYRKPNGTNPSVFSFLNPLSPDIWMYVLLAYLGVS--CVLFVIAR 585

  Fly   323 QSPADQY-MH-----EALQENVWVLISLFTLYITVAIYLCSPLRPRDLSAAFLQSICTLTYSVPT 381
            .||.:.| .|     ..:.||.:.|::.|...:...:...|.|.|:.||...:..|.
Human   586 FSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIW-------- 642

  Fly   382 FIIRTPTLRMRYLYILLAIWGIVTSNLYISRMTSYFTTAPPVRQINTVQDVVEANLRIKMLAIEY 446
                       :.:.|:    |::|  |.:.:.::.|.......|::..|:.      |...|||
Human   643 -----------WFFTLI----IISS--YTANLAAFLTVERMESPIDSADDLA------KQTKIEY 684

  Fly   447  446
            Human   685  684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir56d	NP_611432.1	ATPase-IIIA_H	<312..422	CDD:273731	20/115 (17%)
GRIK3	NP_000822.2	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	4/14 (29%)
		ANF_receptor	55..398	CDD:279440
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	53/293 (18%)
		Lig_chan	564..832	CDD:278489	27/154 (18%)
		Glutamate binding. /evidence=ECO:0000250	690..692

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000