DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11007 and Tmx2

DIOPT Version :9

Sequence 1:	NP_001286617.1	Gene:	CG11007 / 37249	FlyBaseID:	FBgn0034455	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_080144.1	Gene:	Tmx2 / 66958	MGIID:	1914208	Length:	295	Species:	Mus musculus

Alignment Length:	264	Identity:	116/264 - (43%)
Similarity:	170/264 - (64%)	Gaps:	12/264 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LAKPYYWVNILLAISYLLAKKTQFICTRLFILAGEDEACDLDSREVEILFFLLIVVMIRSRKTGS 74
            ||:||..::.||:|::||.:|...||..|.....:...||.|.||||||.||..:||:::|:  |
Mouse    21 LARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRR--S 83

  Fly    75 VTMINYLASSFLYTKVANAILWAYADFRYGLGFLLLCVLVGMVLPEPSYRGPEHITYFRNAQVFE 139
            :|:..::.:.|:::|||||||:...|.|.||.:|.||::..|....|.|.|||:|.|| |.:..:
Mouse    84 ITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYF-NDKTID 147

  Fly   140 EELARDKRTSWLICFYTVWNPSCVNFAPVFAELSAEYNTDHLKFGKIDIGRFPDVAQKYRISDSS 204
            |||.||||.:|::.|:..|:..|.:|||::|:||.:||...|.|||:|:||:.||:.:|::|.|.
Mouse   148 EELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSP 212

  Fly   205 FSRQLPTVILFQQGKETDRRPCVDSKGKLQKFFFSSDNVRATFGLNQLYKEA---------IERL 260
            .:|||||:||||.|||..|||.:|.||:...:.||.:||...|.||:||:.|         .|..
Mouse   213 LTRQLPTLILFQGGKEVIRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKHSKGGDMSEEK 277

  Fly   261 PIAP 264
            |:.|
Mouse   278 PVDP 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11007	NP_001286617.1	TMX2	100..251	CDD:239260	72/150 (48%)
Tmx2	NP_080144.1	TMX2	109..259	CDD:239260	72/150 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	266..295		3/16 (19%)
		Di-lysine motif. /evidence=ECO:0000305	292..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837790
Domainoid	1	1.000	106	1.000	Domainoid score	I6604
eggNOG	1	0.900	-	-		E1_KOG0914
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9317
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3466
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57880
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005620
OrthoInspector	1	1.000	-	-		oto91865
orthoMCL	1	0.900	-	-		OOG6_105435
Panther	1	1.100	-	-	LDO	PTHR15853
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2853
SonicParanoid	1	1.000	-	-		X4598
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790