DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11007 and tmx2a

DIOPT Version :9

Sequence 1:	NP_001286617.1	Gene:	CG11007 / 37249	FlyBaseID:	FBgn0034455	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001103857.1	Gene:	tmx2a / 561718	ZFINID:	ZDB-GENE-050208-95	Length:	301	Species:	Danio rerio

Alignment Length:	244	Identity:	95/244 - (38%)
Similarity:	165/244 - (67%)	Gaps:	3/244 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KPYYWVNILLAISYLLAKKTQFICTRLFILAGEDEACDLDSREVEILFFLLIVVMIRSRKTGSVT 76
            :|||::::|:.:::::.:....:|..|.....:.::|..|.|||||..||..:||:::|:  :||
Zfish    23 RPYYFLSLLMTLAFVIVRCCPGLCEHLPSQREDGDSCAFDWREVEIFMFLGAIVMMKNRR--AVT 85

  Fly    77 MINYLASSFLYTKVANAILWAYADFRYGLGFLLLCVLVGMVLPEPSYRGPEHITYFRNAQVFEEE 141
            :..::.:.||::||||.:|:...|.|:||.:|.|||:..:....|:|.|||:|.|||::.: :||
Zfish    86 VEQHIGNIFLFSKVANVVLFFRVDLRFGLLYLTLCVVFLITCKPPAYMGPENIKYFRDSTI-DEE 149

  Fly   142 LARDKRTSWLICFYTVWNPSCVNFAPVFAELSAEYNTDHLKFGKIDIGRFPDVAQKYRISDSSFS 206
            |.||.|.:|::.||..|:|.|.:|||:||:||.:|....|||||:|||.:..||::|:::.|...
Zfish   150 LQRDSRVTWIVEFYANWSPECQSFAPIFADLSLKYTCLGLKFGKVDIGHYGAVAERYKVNPSPLC 214

  Fly   207 RQLPTVILFQQGKETDRRPCVDSKGKLQKFFFSSDNVRATFGLNQLYKE 255
            :|||::::.|.|:|..|||.||.||:...:.|:.||:...|.||:::::
Zfish   215 KQLPSLLMLQAGRELMRRPLVDKKGRAVSWNFTEDNIIRDFNLNEIFQK 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11007	NP_001286617.1	TMX2	100..251	CDD:239260	67/150 (45%)
tmx2a	NP_001103857.1	TMX2	109..259	CDD:239260	67/150 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	268..301
		Di-lysine motif. /evidence=ECO:0000305	298..301
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581544
Domainoid	1	1.000	102	1.000	Domainoid score	I6816
eggNOG	1	0.900	-	-		E1_KOG0914
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3579
OMA	1	1.010	-	-		QHG57880
OrthoDB	1	1.010	-	-		D1107509at2759
OrthoFinder	1	1.000	-	-		FOG0005620
OrthoInspector	1	1.000	-	-		otm24662
orthoMCL	1	0.900	-	-		OOG6_105435
Panther	1	1.100	-	-	O	PTHR15853
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4598
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770