DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11007 and tmx2b

DIOPT Version :9

Sequence 1:	NP_001286617.1	Gene:	CG11007 / 37249	FlyBaseID:	FBgn0034455	Length:	271	Species:	Drosophila melanogaster
Sequence 2:	NP_001002113.1	Gene:	tmx2b / 415203	ZFINID:	ZDB-GENE-040625-105	Length:	307	Species:	Danio rerio

Alignment Length:	266	Identity:	110/266 - (41%)
Similarity:	169/266 - (63%)	Gaps:	16/266 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LAKPYYWVNILLAISYLLAKKTQFICTRLFILAGEDEACDLDSREVEILFFLLIVVMIRSRKTGS 74
            |.||||..::.::|::::.:|...:|..|.....:..:||.|.||||||.||..:||:::|:  :
Zfish    21 LLKPYYIASLFMSIAFVMIRKMPGVCEHLSTQREDGNSCDFDWREVEILMFLSAIVMMKNRR--A 83

  Fly    75 VTMINYLASSFLYTKVANAILWAYADFRYGLGFLLLCVLVGMVLPEPSYRGPEHITYFRNAQVFE 139
            :|:..::.:..|:.||||.||:...|.|.||.:|.||::..|....|.|.|||:|.||.: :..:
Zfish    84 ITIEQHVGNIILFCKVANVILFFRLDIRLGLLYLTLCIVFLMTCKPPLYMGPEYIKYFSD-KTID 147

  Fly   140 EELARDKRTSWLICFYTVWNPSCVNFAPVFAELSAEYNTDHLKFGKIDIGRFPDVAQKYRISDSS 204
            |||.:|.|.:|::.|:..|:|.|.:||.|:|:||.:||...|||||:||||:.:|::|||:|.|.
Zfish   148 EELEKDHRVTWIVEFFANWSPECQSFASVYADLSLKYNCAGLKFGKVDIGRYGEVSKKYRVSTSP 212

  Fly   205 FSRQLPTVILFQQGKETDRRPCVDSKGKLQKFFFSSDNVRATFGLNQLY---------KEAIERL 260
            .|:|||:::|||.|||..|||.||.||:...:.|:.:|:...|.||:||         ||.:||
Zfish   213 LSKQLPSLVLFQGGKEVMRRPQVDKKGRAVSWTFTEENIIREFNLNELYQKSKKLGKTKEKLER- 276

  Fly   261 PIAPKE 266
               |.|
Zfish   277 ---PSE 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11007	NP_001286617.1	TMX2	100..251	CDD:239260	70/150 (47%)
tmx2b	NP_001002113.1	TMX2	109..259	CDD:239260	70/150 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	268..307		6/16 (38%)
		Di-lysine motif. /evidence=ECO:0000305	304..307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581543
Domainoid	1	1.000	102	1.000	Domainoid score	I6816
eggNOG	1	0.900	-	-		E1_KOG0914
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9317
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3579
OMA	1	1.010	-	-		QHG57880
OrthoDB	1	1.010	-	-		D1107509at2759
OrthoFinder	1	1.000	-	-		FOG0005620
OrthoInspector	1	1.000	-	-		otm24662
orthoMCL	1	0.900	-	-		OOG6_105435
Panther	1	1.100	-	-	LDO	PTHR15853
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2853
SonicParanoid	1	1.000	-	-		X4598
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800