Protein Alignment hpo and KIC1

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_011970.1
• Gene: KIC1 / 856502
• SGDID: S000001144
• Length: 1080
• Species: Saccharomyces cerevisiae
• Alignment Length: 612
• Identity: 171/612 - (27%)
• Similarity: 270/612 - (44%)
• Gaps: 105/612 - (17%)

  Fly    48 LGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEI------IKEISIMQQCDSPYVVRYYGSYFK 106
            :|.|.:|.|||..:.::..:.|||::.::||..|:      |:.::.::|..:  :.||||||.|
Yeast    29 IGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISN--ITRYYGSYLK 91

  Fly   107 QYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNT 171
            ...|||.||:|..||:..::|..|  :.|..|..|:.:.|..|..:|....|||||||||:|:..
Yeast    92 DTSLWIIMEHCAGGSLRSLLRPGK--IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITN 154

  Fly   172 EGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-EEIGYDCVADIWSLGITALEMAEGKPP 235
            ||..||.|||||.|:..|..:|.|:.|||:||||||| |.:.||...||||||||..|:|.|.||
Yeast   155 EGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPP 219

  Fly   236 YGEIHPMRAIFMIPQKPPPSFREPDR-WSTEFIDFVSKCLVKEPDDRATATELLEHEFIR--NAK 297
            |.::..:||:.:|.:..||  |..|| :||...:|::.||.::|.:|.:|.:||:.:|||  .|.
Yeast   220 YCDVEALRAMQLIIKSKPP--RLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKAT 282

  Fly   298 HRSILKPMLEETCAIREQQRANRSFGGVLAASQ-------------------AKSLATQENGMQQ 343
            ..||||.::......|::.:......|.:..::                   .||:|:.:|.:::
Yeast   283 PTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSKPSEAPKPSQNGGGDEAQKSIASNDNEIKR 347

  Fly   344 -------------------HITDN-----AFMEDPGT-----------LVPEKFGEYQQSSASDA 373
                               :|.:|     |..||...           ..|::...|...::.:.
Yeast   348 VNEGDVEMKWDFDSLSSSDYIIENNINLDALAEDNNEWATAQHDLFNYAYPDEDSYYFDPTSHNT 412

  Fly   374 TMIAHAEQGVDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDSGTMVELESNLGTMVINSDS 438
            ....:  ||...|...||.:...|...||...:...|......|...|........|.|
Yeast   413 RPFVY--QGTTIGKGYPGTIAQNSTLNAPVTNNYTNSKYPSKMVAGTTNTSGTHTAGPM------ 469

  Fly   439 DDSTTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDEKPIATEYSPAAAEQQQQQQQQQQQQQQ 503
               |::|..:.:.|:     |.||.|:.........|....|.:.|.:.:........:
Yeast   470 ---TSSKRLESKAPK-----QLLELFEDNEIITAENDVNTEAPKISKSISSLNAGNSSR------ 520

  Fly   504 DEQHLASGANDLNNWEHNMEMQ--FQQISAINQYGLQQHQQQQQVLMAYPLMNEQLIALNNQPNL 566
             :..:.|.:|::|...:|.:|:  ...:|:.|.|       ..|...|.||:..:....:..|..
Yeast   521 -DDFIPSISNEVNGNINNNKMRPHLPPLSSGNNY-------YSQSTPALPLLQTKFNKTSKGPPT 577

  Fly   567 LLSNAAPMG-QQGIPAAAP--AQPPPA 590
            .....||.. :..||...|  |.|.||
Yeast   578 SGLTTAPTSIEIEIPEELPNSALPTPA 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	105/252 (42%)
		S_TKc	42..293	CDD:214567	105/252 (42%)
		Mst1_SARAH	608..655	CDD:288481
KIC1	NP_011970.1	STKc_NAK1_like	21..295	CDD:270822	113/271 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910