Protein Alignment hpo and STK24

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_016876283.1
• Gene: STK24 / 8428
• HGNCID: 11403
• Length: 517
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 173/421 - (41%)
• Similarity: 237/421 - (56%)
• Gaps: 67/421 - (15%)

  Fly    32 ESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPV---ESDLHEIIKEISIMQQCD 93
            ::|...||::|..:.|:|:||:|.|:|.:...:..:||||::.:   |.::.:|.:||:::.|||
Human   100 KNLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 164

  Fly    94 SPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKI 158
            ||||.:|||||.|...|||.|||.|.||..|:  |....|.|.:|||||.:.|:||.|||..:||
Human   165 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDL--LEPGPLDETQIATILREILKGLDYLHSEKKI 227

  Fly   159 HRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLG 223
            ||||||||:||:..|..||||||||||||||..||||.:|||||||||||::..||..|||||||
Human   228 HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLG 292

  Fly   224 ITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELL 288
            |||:|:|.|:||:.|:|||:.:|:||:..||:..  ..:|....:||..||.|||..|.||.|||
Human   293 ITAIELARGEPPHSELHPMKVLFLIPKNNPPTLE--GNYSKPLKEFVEACLNKEPSFRPTAKELL 355

  Fly   289 EHEFI-RNAKHRSILKPML-----------------EETCAIREQQRANRSFGG----VLAASQA 331
            :|:|| ||||..|.|..::                 |::.|..:.|.:..|..|    .:.....
Human   356 KHKFILRNAKKTSYLTELIDRYKRWKAEQSHDDSSSEDSDAETDGQASGGSDSGDWIFTIREKDP 420

  Fly   332 KSLATQENGMQQ----------HITDNAFMEDPGTLVPEKFGEYQQSS----------------- 369
            |:|   |||..|          .|....|.:...|::...|.|.::.|
Human   421 KNL---ENGALQPSDLDRNKMKDIPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAI 482

  Fly   370 --ASDA------TMIAHAEQGVDEGTLGPGG 392
              |.:|      ||:|...|.:...:|..||
Human   483 YLAEEACPGISDTMVAQLVQRLQRYSLSGGG 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	138/257 (54%)
		S_TKc	42..293	CDD:214567	136/253 (54%)
		Mst1_SARAH	608..655	CDD:288481
STK24	XP_016876283.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D967913at2759
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920