DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hpo and YDA

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	151/537 - (28%)
Similarity:	226/537 - (42%)	Gaps:	107/537 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LGEGSYGSVYKAVHKESSSIVAIKLVPVESD-------LHEIIKEISIMQQCDSPYVVRYYGSYF 105
            ||.||:|.||...:.||..:.|:|.|.:.||       ..::.:|||::.:.....:|:||||..
plant   406 LGMGSFGHVYLGFNSESGEMCAMKEVTLCSDDPKSRESAQQLGQEISVLSRLRHQNIVQYYGSET 470

  Fly   106 KQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLN 170
            ....|:|.:||...||:..::: ......|:.|.......|.||.|||.:..:|||||.||||::
plant   471 VDDKLYIYLEYVSGGSIYKLLQ-EYGQFGENAIRNYTQQILSGLAYLHAKNTVHRDIKGANILVD 534

  Fly   171 TEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEI-GYDCVADIWSLGITALEMAEGKP 234
            ..|..|:||||:|..:| ..:...:..|:|:|||||||:.. |.:...||||||.|.||||..||
plant   535 PHGRVKVADFGMAKHIT-AQSGPLSFKGSPYWMAPEVIKNSNGSNLAVDIWSLGCTVLEMATTKP 598

  Fly   235 PYGEIHPMRAIFMI-PQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKH 298
            |:.:...:.|:|.| ..|..|..  ||..|.|..|||.|||.:.|.:|.||.:||:|.|:||
plant   599 PWSQYEGVPAMFKIGNSKELPDI--PDHLSEEGKDFVRKCLQRNPANRPTAAQLLDHAFVRN--- 658

  Fly   299 RSILKPMLEETCAIREQQRANRSFGGVLAASQAKSLATQENGMQQHITDNAFMEDPGTLVPEKFG 363
               :.||.....:....:..|      :|:|..:||            |.........|..|...
plant   659 ---VMPMERPIVSGEPAEAMN------VASSTMRSL------------DIGHARSLPCLDSEDAT 702

  Fly   364 EYQQSSASDATMIAHAEQGVDEG-----TLGPGGLRNLSKAAAPA------------AASSAASP 411
            .|||             :|:..|     :..|   ||:|...:|.            :...:.||
plant   703 NYQQ-------------KGLKHGSGFSISQSP---RNMSCPISPVGSPIFHSHSPHISGRRSPSP 751

  Fly   412 LDMPAVDSGTMVELESNLGTMVINSDSDDSTTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDE 476
            :..|...||:...|....|.:..:...  .||.              .||......:...|.|
plant   752 ISSPHALSGSSTPLTGCGGAIPFHHQR--QTTV--------------NFLHEGIGSSRSPGSG-- 798

  Fly   477 KPIATEYSPAAAEQQQQQQQQQQQQQQDEQHLASGANDLNNWEHNMEMQ-FQQISAINQYGLQQH 540
               ...|:.:..::..:||.:.:...:...|:.        |::|..:| ....:..||..|..|
plant   799 ---GNFYTNSFFQEPSRQQDRSRSSPRTPPHVF--------WDNNGSIQPGYNWNKDNQPVLSDH 852

  Fly   541 QQQQQVLMAYPLMNEQL 557
            ..||       |::|.|
plant   853 VSQQ-------LLSEHL 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	99/253 (39%)
		S_TKc	42..293	CDD:214567	99/253 (39%)
		Mst1_SARAH	608..655	CDD:288481
YDA	NP_001319310.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910