DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hpo and MAPKKK15

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001330365.1	Gene:	MAPKKK15 / 835600	AraportID:	AT5G55090	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	435	Identity:	119/435 - (27%)
Similarity:	188/435 - (43%)	Gaps:	85/435 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VDMKSPNISS--------SCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSS 66
            |...|.:|||        |||.    .:.|::.::.|        .:|.||..:|...: ..|..
plant    40 VHFLSLSISSVFFVPLFFSCSV----SMEEQNWIRGP--------IIGRGSTATVSLGI-TNSGD 91

  Fly    67 IVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQ------YDLWICMEYCGAGSVSDI 125
            ..|:|.....|... :.:|.||:.:..|||:|:|.||...:      |:|  .|||...||:.|:
plant    92 FFAVKSAEFSSSAF-LQREQSILSKLSSPYIVKYIGSNVTKENDKLMYNL--LMEYVSGGSLHDL 153

  Fly   126 MRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTM 190
            ::.....|.|..|.:.....|:||:|||.:..:|.|:|:.|:::..| .||:.|.|.|..:.:.
plant   154 IKNSGGKLPEPLIRSYTRQILKGLMYLHDQGIVHCDVKSQNVMIGGE-IAKIVDLGCAKTVEEN- 216

  Fly   191 AKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHP-MRAIFMI------ 248
             :.....|||.:|:|||.........||:|:||.|.:|||.|..|:.|::. :.||:.|
plant   217 -ENLEFSGTPAFMSPEVARGEEQSFPADVWALGCTVIEMATGSSPWPELNDVVAAIYKIGFTGES 280

  Fly   249 PQKPPPSFREPDRW-STEFIDFVSKCLVKEPDDRATATELLEHEF--------------IRNAKH 298
            |..|.        | |.:..||:.|||.|:|..|.|..|||:|.|              :.::..
plant   281 PVIPV--------WLSEKGQDFLRKCLRKDPKQRWTVEELLQHPFLDEEDNDSDQTGNCLNSSSP 337

  Fly   299 RSILKPMLEETCA------IREQQR---ANRS----FGGVLAASQAKSLATQENGMQQHITDNAF 350
            .::|.....:.|.      |:|...   ||.:    ....|...:.|.||..|:..:.....|.:
plant   338 STVLDQRFWDLCETSRSRFIKEDHEDPFANSTNFLWDDDSLPGDRIKKLAGDESSGEPDWETNGW 402

  Fly   351 MEDPGTLVPEKFGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRN 395
            :|..|.:  ||..|.:..:..:||.:...|:.|       ||..|
plant   403 IEVRGEI--EKRNEEEDENCVEATSLEEDEEEV-------GGFEN 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	86/282 (30%)
		S_TKc	42..293	CDD:214567	85/278 (31%)
		Mst1_SARAH	608..655	CDD:288481
MAPKKK15	NP_001330365.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910