DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hpo and MEKK3

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_192587.1	Gene:	MEKK3 / 826406	AraportID:	AT4G08470	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	286	Identity:	103/286 - (36%)
Similarity:	147/286 - (51%)	Gaps:	26/286 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KKLSEESLLQPPEKVFDIM-----YKLGEGSYGSVYKAVHKESSSIVAIKLVPV-------ESDL 79
            :||....|::...|..||.     ..||.|||.|||:|: .|.....|:|.|.:       :..:
plant   283 RKLMRNKLIENFRKPEDITSWLKGQLLGRGSYASVYEAI-SEDGDFFAVKEVSLLDKGIQAQECI 346

  Fly    80 HEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSD 144
            .::..||:::.|.....:|||.|:......|:|.:|....|||..:  ..:..|:...::.....
plant   347 QQLEGEIALLSQLQHQNIVRYRGTAKDVSKLYIFLELVTQGSVQKL--YERYQLSYTVVSLYTRQ 409

  Fly   145 TLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGV--AGQLTDTMAKRNTVIGTPFWMAPEV 207
            .|.||.|||.:..:|||||.||:|::..|..||||||:  |.:..|.|:.:    ||.|||||||
plant   410 ILAGLNYLHDKGFVHRDIKCANMLVDANGTVKLADFGLAEASKFNDIMSCK----GTLFWMAPEV 470

  Fly   208 I---EEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDF 269
            |   :..|....|||||||.|.|||..|:.||.::.|::|.|.|.:...|..  ||..|.:...|
plant   471 INRKDSDGNGSPADIWSLGCTVLEMCTGQIPYSDLKPIQAAFKIGRGTLPDV--PDTLSLDARHF 533

  Fly   270 VSKCLVKEPDDRATATELLEHEFIRN 295
            :..||...|::|.||.|||.|.|:.|
plant   534 ILTCLKVNPEERPTAAELLHHPFVIN 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	98/271 (36%)
		S_TKc	42..293	CDD:214567	97/267 (36%)
		Mst1_SARAH	608..655	CDD:288481
MEKK3	NP_192587.1	PKc_like	302..557	CDD:328722	95/263 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910