DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hpo and stk26

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_001164989.1	Gene:	stk26 / 733529	XenbaseID:	XB-GENE-982067	Length:	413	Species:	Xenopus tropicalis

Alignment Length:	403	Identity:	161/403 - (39%)
Similarity:	236/403 - (58%)	Gaps:	49/403 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 PEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPV---ESDLHEIIKEISIMQQCDSPYVVR 99
            ||::|..:.::|:||:|.|:|.:...:..:||||::.:   |.::.:|.:||:::.|||||||.:
Frog    20 PEELFTKLERIGKGSFGEVFKGIDNRTQHVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTK 84

  Fly   100 YYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKA 164
            |||||.|...|||.|||.|.||..|::|:  ....|.:|||:|.:.|:||.|||...||||||||
Frog    85 YYGSYLKGTKLWIIMEYLGGGSALDLLRV--GPFDEFQIATMLKEILKGLDYLHSENKIHRDIKA 147

  Fly   165 ANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEM 229
            ||:||:.:|..||||||||||||||..||||.:|||||||||||::..||..||||||||||:|:
Frog   148 ANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIEL 212

  Fly   230 AEGKPPYGEIHPMRAIFMIPQKPPPS----FREPDRWSTEFIDFVSKCLVKEPDDRATATELLEH 290
            |:|:||..::||||.:|:||:..|||    |.:|      |.:||..||.|:|..|.||.|||:|
Frog   213 AKGEPPNSDMHPMRVLFLIPKNNPPSLTGDFSKP------FKEFVDACLNKDPSFRPTARELLKH 271

  Fly   291 EFI-RNAKHRSILKPMLE---------------ETCAIREQQRANR-----SFGGVLAASQAKSL 334
            ::| :|||..|.|..:::               :........:.|.     ||..|....::|
Frog   272 KYIVKNAKRTSYLTELIDRFKRWKAEGHSDSGSDDSDTESNNKENHTHPEWSFTTVRKKPESK-- 334

  Fly   335 ATQENGMQQHITDNAFMEDPGTLVPEKFGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRNLSKA 399
             |.:||..|.:...  :.....::...|.|.:|...:: |:..:|.:.:::..       |:::|
Frog   335 -TMQNGTDQDLVKT--LSSLSAIISPVFAELKQQDRNN-TVRKNAIEELEKSI-------NVAEA 388

  Fly   400 AAPAAASSAASPL 412
            ..|.........|
Frog   389 TYPGITDKMVKKL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	137/261 (52%)
		S_TKc	42..293	CDD:214567	135/257 (53%)
		Mst1_SARAH	608..655	CDD:288481
stk26	NP_001164989.1	STKc_MST3_like	22..295	CDD:270786	141/280 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D967913at2759
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010