Protein Alignment hpo and Stk3

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_038935793.1
• Gene: Stk3 / 65189
• RGDID: 68412
• Length: 532
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 311/666 - (46%)
• Similarity: 388/666 - (58%)
• Gaps: 151/666 - (22%)

  Fly    12 MKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVE 76
            |:.|....|    |||||||:||.:.||:|||::.||||||||||:||:||||..:||||.||||
  Rat     1 MEQPPAPKS----KLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVE 61

  Fly    77 SDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATI 141
            |||.||||||||||||||||||:|||||||..||||.||||||||||||:|||.|||||||||||
  Rat    62 SDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATI 126

  Fly   142 LSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 206
            |..||:||.|||..|||||||||.||||||||:||||||||||||||||||||||||||||||||
  Rat   127 LKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPE 191

  Fly   207 VIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVS 271
            ||:||||:|||||||||||::|||||||||.:|||||||||||..|||:||:|:.||.:|.|||.
  Rat   192 VIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVK 256

  Fly   272 KCLVKEPDDRATATELLEHEFIRNAKHRSILKPMLEETCAIREQQRANRSFGGVLAASQAKSLAT 336
            |||||.|:.|||||:||:|.||:|||..|||:.::.|...|:.::.          ..|.:.|..
  Rat   257 KCLVKSPEQRATATQLLQHPFIKNAKPVSILRELITEGMEIKAKRH----------EEQQRELED 311

  Fly   337 QENGMQQHITDNAFMEDPGTLVPEKFGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRNLSKAAA 401
            :|....:...|:                        .||:..:.:||  ||:           .|
  Rat   312 EEENSDEDELDS------------------------HTMVKTSSEGV--GTM-----------RA 339

  Fly   402 PAAASSAASPLDMPAVDSGTMVE-----LESNLGTMVINS---DSDDSTTAKNNDDQKPRNRYRP 458
            .:..|..|.          ||:|     |||:||||||||   :.:|.|..:|....:.:   ||
  Rat   340 TSTMSEGAQ----------TMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQ---RP 391

  Fly   459 QFLEHFDR---KNAGDGRGDEK-----PIATEYSPAAAEQQQQQQQQQQQQQQDEQHLASGANDL 515
            .|:::||:   ||......|:.     |::....|
  Rat   392 SFMDYFDKQDFKNKSHENCDQSMREPCPMSNNVFP------------------------------ 426

  Fly   516 NNWEHNMEMQFQQISAINQYGLQQHQQQQQVLMAYPLMNEQLIALNNQPNLLLSNAAPMGQQGIP 580
            :||....:..|..|..:       ....:..:|..|..|...:..::.|.|..||..|
  Rat   427 DNWRVPQDGDFDFIEDL-------RLAVKAKVMPKPPANGTELLTHSLPPLPSSNPKP------- 477

  Fly   581 AAAPAQPPPAYQNQHMHTQSHAYVEGEFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKR 645
                            |.:           ||.|:.::|..||..:|..||.|||:|:::|:|||
  Rat   478 ----------------HKR-----------LKNLSLEELQMRLKALDPMMEREIEELHQRYSAKR 515

  Fly   646 QPIVDAMNAKRKRQQN 661
            |||:|||:||::||||
  Rat   516 QPILDAMDAKKRRQQN 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	207/254 (81%)
		S_TKc	42..293	CDD:214567	204/250 (82%)
		Mst1_SARAH	608..655	CDD:288481	23/46 (50%)
Stk3	XP_038935793.1	STKc_MST1_2	23..278	CDD:132943	207/254 (81%)
		Mst1_SARAH	481..525	CDD:402983	23/43 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343251
Domainoid	1	1.000	428	1.000	Domainoid score	I579
eggNOG	1	0.900	-	-		E1_KOG0574
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48420
Inparanoid	1	1.050	553	1.000	Inparanoid score	I1083
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D247842at33208
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	1	1.000	-	-		otm46401
orthoMCL	1	0.900	-	-		OOG6_102280
Panther	1	1.100	-	-	LDO	PTHR48015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1715
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760