Protein Alignment hpo and msn

DIOPT Version :10

• Sequence 1: NP_611427.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_524679.3
• Gene: msn / 44030
• FlyBaseID: FBgn0010909
• Length: 1504
• Species: Drosophila melanogaster
• Alignment Length: 629
• Identity: 189/629 - (30%)
• Similarity: 293/629 - (46%)
• Gaps: 116/629 - (18%)

  Fly    14 SPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESD 78
            :|:::.|.....|      :.|:.|..:|:::..:|.|:||.|||..|.::..:.|||::.|..|
  Fly    10 APSVNCSLDDIDL------TALKDPAGIFELIEVVGNGTYGQVYKGRHTKTGQLAAIKVMDVTED 68

  Fly    79 LHEIIK-EISIMQQ-CDSPYVVRYYGSYFKQY------DLWICMEYCGAGSVSDIMRLRK-KTLT 134
            ..|.|| ||::::: .:...:..|||::.|:.      .||:.|||||||||:|:::..| ::|.
  Fly    69 EEEEIKLEINVLKKYSNHRNIATYYGAFIKKSPPGKDDQLWLVMEYCGAGSVTDLVKSTKGQSLK 133

  Fly   135 EDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGT 199
            |:.||.|..:.|:||.|||..:.||||||..|:||......||.||||:.||..|:.:|||.|||
  Fly   134 EEWIAYICREILRGLSYLHSNKVIHRDIKGQNVLLTDNAEVKLVDFGVSAQLDRTIGRRNTFIGT 198

  Fly   200 PFWMAPEVI-----EEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREP 259
            |:|||||||     .:..||..:|:||||||||||||.:||..::|||||:|:||:..||..:.
  Fly   199 PYWMAPEVIACDENPDATYDNRSDLWSLGITALEMAESQPPLCDLHPMRALFLIPRNSPPRLKS- 262

  Fly   260 DRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIR----NAKHRSILKPMLEETCAIR--EQQRA 318
            .:||.:|..|:...|||:...|.....||:|.||:    :.:.|..||..::. |..|  |::|.
  Fly   263 KKWSKKFHGFIDTVLVKDYHQRPYTENLLKHGFIKDQPTDRQVRIQLKDHIDR-CKKRKQEKERE 326

  Fly   319 NRSFGGVLAASQAKSLATQENGMQQ-----HITDNAFMEDPGTLVPEKFGEYQ-----QSSASDA 373
            :..:.|.........||.:.:.:.|     .:..|......|.|..|:..::.     |:.|:.|
  Fly   327 DYRYSGSDNDDDEPQLAGEHSSIVQAPGGDTLRRNFQQIQEGRLAAEQQQQHHLMAQAQAQAAAA 391

  Fly   374 TMIAHAEQGVDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDSGTMVELESNLGTMVINSDS 438
            ...|.|:..:.:        :....|||.|||:.||......|..:
  Fly   392 HAAAQAQAQLQQ--------QQQQAAAAAAAAAHAAQQAQQAAQQA------------------- 429

  Fly   439 DDSTTAKNNDDQKPRNRYR----------PQFL------EHFDRKNAGDGRGDEKPIATEYSPAA 487
             .:...:.|...||.:|.:          ||.|      .|.:|           |:..  :|..
  Fly   430 -QAQQPQANRQPKPPSRQQVEEPGPPARPPQRLIVVPDPPHANR-----------PLPP--TPKC 480

  Fly   488 AEQQQQQQQQQQQQQQDEQHLASGANDLNNWEHNMEMQFQQISAINQYGLQQHQQQQQVLMAYPL 552
            .|...|..||||:..|            ||::.::..:..:.......|.|..|||.|
  Fly   481 GEPAGQTPQQQQRNSQ------------NNFKPSLPPRRPEPQPQTAAGGQGSQQQAQ------- 526

  Fly   553 MNEQLIALNNQPNLLLSNAAPMGQQGIPAAAPAQPPPAYQNQHM 596
              .:....||:.:..||::......|..::.||...|...|.|:
  Fly   527 --PEAPPRNNRQSSGLSSSGGSASGGGGSSKPAAALPQQSNNHL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_611427.1	STKc_MST1_2	38..293	CDD:132943	118/268 (44%)
		SARAH_Hpo	606..661	CDD:439183
msn	NP_524679.3	STKc_myosinIII_N_like	25..296	CDD:270785	119/271 (44%)
		CNH	1183..1484	CDD:214481