Protein Alignment hpo and hppy

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Alignment Length: 680
• Identity: 197/680 - (28%)
• Similarity: 302/680 - (44%)
• Gaps: 159/680 - (23%)

  Fly    17 ISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVE--SDL 79
            ::::.|......||.:...:.|:..::::.|:|.|:||.||||...:|:.:.|||::.:|  .|:
  Fly     1 MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDI 65

  Fly    80 HEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSD 144
            ..|.:||.:|:.|..|.::.|||||.::..||||||:||.||:.||.:: ...|||.:||.:..:
  Fly    66 QIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQV-TGPLTEVQIAYMCRE 129

  Fly   145 TLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI- 208
            ||:||.|||...|:|||||.|||||...|..|||||||:.|:|.|:.||.:.||||:||||||.
  Fly   130 TLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAA 194

  Fly   209 --EEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQK--PPPSFREPDRWSTEFIDF 269
              .:.||:.:.|||:.||||:|:||.:||..::|||||:|::.:.  .||:....|:||..|.:|
  Fly   195 VERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNF 259

  Fly   270 VSKCLVKEPDDRATATELLEHEFIRNAKHRSILKPML-----------------EETCAIREQQR 317
            :...|.|.|..|.||..||:|.|::......:.|.:|                 ||:.|...|:.
  Fly   260 IKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRI 324

  Fly   318 ANR---SFGGVLAASQAKSLATQENGMQQHITDNAFMEDPGTLVPEKFGEYQQSSASDATMIAHA 379
            |::   ...||.|.:.     |.:.||..:.|.|.....|.||            .||.:::
  Fly   325 ASKMTSRTNGVPAQNH-----TLKTGMTTNSTWNERSSSPETL------------PSDMSLL--- 369

  Fly   380 EQGVDE-----------------------------GTLGPGGLRNLSKAAAPAAASSAASPLDMP 415
             |.:||                             |..|.||...:...|..|||:.::|
  Fly   370 -QYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSS----- 428

  Fly   416 AVDSGTMVELESNLGTMVINSDSDDSTTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDEKPIA 480
                       |:.|..|        .|..:...|..::.:.|..|.
  Fly   429 -----------SSGGATV--------GTTHHQHQQHHQHHHHPNHLH------------------ 456

  Fly   481 TEYSPAAAEQQQQQQQQQQQQQQDEQH------LASGANDLNNWEHNMEMQFQQISAINQY-GLQ 538
             ::......||||||..|..||:...|      ::||....|....:.......:..::.| |::
  Fly   457 -QHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMR 520

  Fly   539 QHQQQQQVL---MAYPLMN----------EQL----IALNNQPNLLLSNAAPMGQ---QGIPAAA 583
            .|......:   |...:.|          ::|    :|:||....:..|.:..|.   .|..|:|
  Fly   521 SHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASA 585

  Fly   584 -----------PAQPPPAYQNQHMHTQSHA 602
                       .|....|.|..|.|..|::
  Fly   586 AHYLRYSSNYRSAAAAQASQAAHPHVNSNS 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	121/261 (46%)
		S_TKc	42..293	CDD:214567	120/257 (47%)
		Mst1_SARAH	608..655	CDD:288481
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	120/258 (47%)
		S_TKc	26..283	CDD:214567	120/257 (47%)
		CNH	869..1184	CDD:279162

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438532
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840