Protein Alignment hpo and Map4k1

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001099713.1
• Gene: Map4k1 / 292763
• RGDID: 1305463
• Length: 827
• Species: Rattus norvegicus
• Alignment Length: 622
• Identity: 176/622 - (28%)
• Similarity: 282/622 - (45%)
• Gaps: 148/622 - (23%)

  Fly    33 SLLQP------PEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVE--SDLHEIIKEISIM 89
            :|:.|      |.:.:|::.:||.|:||.|:||..|.|..:||:|:|.:|  .|:..:.|||.::
  Rat     2 ALVDPDIFNKDPREHYDLLQRLGGGTYGEVFKARDKVSKDLVALKMVKMEPDDDVSTLQKEILML 66

  Fly    90 QQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHL 154
            :.|....:|.|:|||.....||||||:|||||:.||.:: ..:|:|.:|:.:..:.||||.|||.
  Rat    67 KSCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQV-TGSLSELQISYVCREVLQGLAYLHS 130

  Fly   155 RRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE---EIGYDCV 216
            ::|||||||.||||:|..|..||||||::.|:..|:|:|.:.||||:||||||..   :.||:.:
  Rat   131 QKKIHRDIKGANILINDSGEVKLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNEL 195

  Fly   217 ADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQK--PPPSFREPDRWSTEFIDFVSKCLVKEPD 279
            .|||||||||:|:||.:||..::||:|.:|::.:.  .||..:|..:||:.|.:||...|.|...
  Rat   196 CDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSSSFHNFVKVTLTKNSK 260

  Fly   280 DRATATELLEHEFI-RNAKHRSILKPMLEETCAIREQQRANRSFGGVLAASQAKSLATQENGMQQ 343
            .|.:||::|.|:.: :...:|.::..:|::                         :.....|:..
  Rat   261 KRPSATKMLSHQLVSQPGLNRGLILDLLDK-------------------------MKNPGKGLPV 300

  Fly   344 HITDNAFMEDPGTLVPEKF-GEYQQSSAS--DATMI-AHAE----------QGVDEGTLGPGG-L 393
            .|.|..  .:|...:|.:. ..|:.||..  ||... .|.|          ...|...|.|.. .
  Rat   301 EIEDEE--PEPPPAIPRRIRSTYRASSLGIPDADCCRRHMEFQRPRCVECRSQADTVLLQPSADF 363

  Fly   394 RNLSKAAAPAAASSAASPLDMPAVDSGTMVELESNLGTMVINSDSDDSTTAKNNDDQ-------- 450
            |:.|..:..:.:......:|:||........|...   ..|.|.|||.:....:|.|
  Rat   364 RSTSPRSQLSDSDDDYDDVDIPAPSENLPPPLPPK---PKIRSPSDDGSGGVRDDGQLSPGVLVR 425

  Fly   451 ----KPRNRYRPQFLEHFDRKNAGDGRGDEKPIATE------YSPAAAE----------QQQQQQ 495
                .|....||           |.......|..|.      ::|||.|          :::.::
  Rat   426 CASGPPPRIPRP-----------GPPPATRSPHLTARSDPSLWNPAAPEPGQPPLLPPRKEKMRK 479

  Fly   496 QQQQQQQQDE----------------------------QHLASGANDLNNWEHNMEMQFQQISAI 532
            :.:.:::::|                            |||..||.:
  Rat   480 KMENEKRREEYTLLVKLFNGCPLQIHSTAAWTHPSTKDQHLLLGAEE------------------ 526

  Fly   533 NQYGLQQHQQQQQVLMAYPLMNEQLIALNNQPNLLLS 569
            ..:.|.::.|:..:.|.:|.....|..:|   |||:|
  Rat   527 GIFILNRNDQEATLEMIFPGRTTWLYCIN---NLLMS 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	118/261 (45%)
		S_TKc	42..293	CDD:214567	117/257 (46%)
		Mst1_SARAH	608..655	CDD:288481
Map4k1	NP_001099713.1	STKc_MAP4K3_like	16..274	CDD:270788	117/258 (45%)
		S_TKc	17..274	CDD:214567	117/257 (46%)
		CNH	506..813	CDD:214481	15/76 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910