DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hpo and ppk11

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_594517.1	Gene:	ppk11 / 2541473	PomBaseID:	SPAC2C4.14c	Length:	312	Species:	Schizosaccharomyces pombe

Alignment Length:	272	Identity:	124/272 - (45%)
Similarity:	179/272 - (65%)	Gaps:	5/272 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LGEGSYGSVYKAVHKESSSIVAIKLVPVES---DLHEIIKEISIMQQCDSPYVVRYYGSYFKQYD 109
            :|:||:|||::|...|||.|||:|:|.:::   .:..:.:||:.:...:|.::.:||.|:...:.
pombe    12 IGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQEINFLIDLNSVHITKYYASFVDGFR 76

  Fly   110 LWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGY 174
            |||.||||..||..|:::| ..|.:|..||.::...|:.|||||.:.|:||||||||||...:|.
pombe    77 LWITMEYCDGGSCLDLLKL-SGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMKDGL 140

  Fly   175 AKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEI 239
            .|||||||:|||.....|.:..:||||||||||:::.||:..||||||||||.|:|.|:|||..|
pombe   141 VKLADFGVSGQLESLRDKNDDFVGTPFWMAPEVVKQTGYNYKADIWSLGITAYELATGEPPYSGI 205

  Fly   240 HPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKHRSILKP 304
            |||:.:.:||:..|||. |..::|..|.||||.||.|.|.|||||..|.:|:||:.....:.:|.
pombe   206 HPMKVLLLIPKHSPPSL-ERSKFSRAFCDFVSNCLKKNPKDRATAEYLSKHKFIKKYCPNTSVKE 269

  Fly   305 MLEETCAIREQQ 316
            ::......:|.:
pombe   270 VVASYAKWKESE 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	120/247 (49%)
		S_TKc	42..293	CDD:214567	120/247 (49%)
		Mst1_SARAH	608..655	CDD:288481
ppk11	NP_594517.1	STKc_MST3_like	4..278	CDD:270786	123/267 (46%)
ppk11	NP_594517.1	S_TKc	6..258	CDD:214567	120/247 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910