DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hpo and byr2

DIOPT Version :9

Sequence 1:	NP_001261092.1	Gene:	hpo / 37247	FlyBaseID:	FBgn0261456	Length:	669	Species:	Drosophila melanogaster
Sequence 2:	NP_595714.2	Gene:	byr2 / 2540612	PomBaseID:	SPBC1D7.05	Length:	659	Species:	Schizosaccharomyces pombe

Alignment Length:	302	Identity:	101/302 - (33%)
Similarity:	160/302 - (52%)	Gaps:	21/302 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIVAIKL 72
            |.::..||...:|.:......|.|::..|..:.:...:  :|.||:|.||..::..|..::|:|.
pombe   362 SFIEQPSPISPTSTTSEDTNTLEEDTDDQSIKWIRGAL--IGSGSFGQVYLGMNASSGELMAVKQ 424

  Fly    73 VPVES-----DLH-----EIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMR 127
            |.::|     |.|     .:..||:::|:....::|:|.||......|.|.:||...|||:.::.
pombe   425 VILDSVSESKDRHAKLLDALAGEIALLQELSHEHIVQYLGSNLNSDHLNIFLEYVPGGSVAGLLT 489

  Fly   128 LRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQL------ 186
            : ..:..|..:...:..||:||.|||.|..:|||||.||||::.:|..|::|||::.:|
pombe   490 M-YGSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNSTS 553

  Fly   187 TDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQK 251
            |.|...|.:..|:.|||||||:::..:....||||||...:||...|.||.....|:|||.|.:.
pombe   554 TKTGGARPSFQGSSFWMAPEVVKQTMHTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQAIFRIGEN 618

  Fly   252 PPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI 293
            ..|.|  |...|:..|||:.|....:.:.|.||:|||.|.|:
pombe   619 ILPEF--PSNISSSAIDFLEKTFAIDCNLRPTASELLSHPFV 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	93/270 (34%)
		S_TKc	42..293	CDD:214567	93/266 (35%)
		Mst1_SARAH	608..655	CDD:288481
byr2	NP_595714.2	PKc_like	393..658	CDD:304357	93/269 (35%)
byr2	NP_595714.2	Pkinase	394..658	CDD:278497	93/268 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910