Protein Alignment hpo and map4k4

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_021334466.1
• Gene: map4k4 / 103908625
• ZFINID: ZDB-GENE-030131-6722
• Length: 1006
• Species: Danio rerio
• Alignment Length: 512
• Identity: 150/512 - (29%)
• Similarity: 232/512 - (45%)
• Gaps: 103/512 - (20%)

  Fly   114 MEYCGAGSVSDIMRLRK-KTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKL 177
            ||:|||||::|:::..| .||.||.||.|..:.|:||.:||....||||||..|:||......||
Zfish     1 MEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHAHHVIHRDIKGQNVLLTENAEVKL 65

  Fly   178 ADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----EEIGYDCVADIWSLGITALEMAEGKPPYG 237
            .||||:.||..|:.:|||.||||:|||||||     .:..||..:|:||.||||:|||||.||..
Zfish    66 VDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLC 130

  Fly   238 EIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFIRNAKH---- 298
            ::|||||:|:||:.|||..:. .:||.:|..|:..||||....|....:||:|.|||:..:
Zfish   131 DMHPMRALFLIPRNPPPRLKS-KKWSKKFFSFIEGCLVKNYTQRPPTDQLLKHPFIRDQPNERQV 194

  Fly   299 RSILKPMLEETCAIR-EQQRANRSFGGVLAASQAKSLATQENGMQQHITDNAFMEDPG-TLVPEK 361
            |..||..|:.....| |:......:.|        |...:|...:|....::.:..|| :.:...
Zfish   195 RIQLKDHLDRCRKKRGEKDETEYEYSG--------SEEEEEESQEQEGEPSSIVNVPGESTLRRD 251

  Fly   362 FGEYQQSSASDATMIAHAEQGVDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDSGTMVELE 426
            |...||.: .:.:.....:|.:.|..|
Zfish   252 FIRLQQEN-KERSEALRRQQLLQEQQL-------------------------------------- 277

  Fly   427 SNLGTMVINSDSDDSTTAKNNDDQKPRNRYRPQFLEHFDRKNAGDGRGDEKPIATEYSPAAAEQQ 491
                                    :.:..|:.|.|.  :|:...:.:.:::....|......|.:
Zfish   278 ------------------------REQEEYKRQLLA--ERQKRIEQQKEQRRRLEEQQRREREMR 316

  Fly   492 QQQQQQQQQQQQDEQHLASGANDLNNWE---HNMEMQFQQISAINQYGLQQHQQQQQVLMAYPLM 553
            :||:::|::::|:|:............|   ...|.:.::.....:|..:|.:::|:.|   .::
Zfish   317 RQQEREQRRREQEEKRRVEELERRRKEEEERRRAEEEKRRADREQEYIRRQLEEEQRHL---EIL 378

  Fly   554 NEQLIALNNQPNLLLSNAAPMGQQGIPAAA------PAQPPPA---YQNQHMHTQSH 601
            .:||  |:.|..||:........||.|.||      ||.||.|   :.|.....|||
Zfish   379 QQQL--LHEQAMLLVDERHRRNVQGSPQAAVLQKQPPAVPPRASEPFSNGSASEQSH 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	92/184 (50%)
		S_TKc	42..293	CDD:214567	92/184 (50%)
		Mst1_SARAH	608..655	CDD:288481
map4k4	XP_021334466.1	PKc_like	<1..209	CDD:328722	99/208 (48%)
		CNH	688..986	CDD:214481

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000