Protein Alignment hpo and taok2b

DIOPT Version :9

• Sequence 1: NP_001261092.1
• Gene: hpo / 37247
• FlyBaseID: FBgn0261456
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_009304676.1
• Gene: taok2b / 100151551
• ZFINID: ZDB-GENE-110603-3
• Length: 1247
• Species: Danio rerio
• Alignment Length: 770
• Identity: 204/770 - (26%)
• Similarity: 318/770 - (41%)
• Gaps: 168/770 - (21%)

  Fly     4 PEVTSVVDMKSPNISSSCSFFKLKKLSEESLLQPPEKVFDIMYKLGEGSYGSVYKAVHKESSSIV 68
            |.......:|.|.::.  .|:|          :.|||:|..:.::|.||:|:||.|....::.:|
Zfish     2 PSSVRAGSLKDPEVAE--LFYK----------EDPEKLFTDLREIGHGSFGAVYFAHDIRTNEVV 54

  Fly    69 AIKLVPV-----ESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRL 128
            |||.:..     .....:||||:..:|:...|..|.|.|.|.:::..|:.|||| .||.||::.:
Zfish    55 AIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPNTVEYRGCYLREHTAWLVMEYC-LGSASDLLEV 118

  Fly   129 RKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKR 193
            .||.|.|.|||.|....||||||||....||||:||.||||...|..||.|||.|    ..:|..
Zfish   119 HKKPLQEVEIAAITHGALQGLVYLHSHNMIHRDVKAGNILLTEPGQVKLGDFGSA----SIVAPA 179

  Fly   194 NTVIGTPFWMAPEVI---EEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPS 255
            |:.:|||:|||||||   :|..||...|:||||||.:|:||.|||...::.|.|::.|.|...|.
Zfish   180 NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPV 244

  Fly   256 FREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEF-----------------------IRNAK 297
            . :.:.||..|.:||..||.|...||.|:..||:|.|                       :.|.:
Zfish   245 L-QSNHWSDYFRNFVDSCLQKISQDRPTSDVLLKHHFLCRERPVTVVMDLIARTKDAVRELDNLQ 308

  Fly   298 HRSILKPMLEET--------------CAIREQQRANRSFG--------------GVLAASQAKSL 334
            :|.:.|.:.:||              |..::.::.....|              .:.|:||:.|:
Zfish   309 YRKMKKILFQETHNGPATEGTEEEESCVFQDVEQYMLRTGTVNSMESSHSLPSMSISASSQSSSV 373

  Fly   335 ATQENG---------MQ--QH-ITDNA-----------FMEDPGTLVPEKFGEYQQS-------- 368
            .:..:|         ||  :| :|.|:           ..:||  ..||...:.||.
Zfish   374 NSLADGSDDSGEMAMMQEGEHTVTSNSSVLHKALNHDNIYDDP--YQPEMDSQQQQQQGPSGGRR 436

  Fly   369 -----------SASDAT-MIAHAEQG--VDEGTLGPGGLRNLSKAAAPAAASSAASPLDMPAVDS 419
                       :||..| .|...|||  :.|...|...:|...:....|..:...:.:|
Zfish   437 RRGRDHFATIRTASLVTRQIQEHEQGSALREQMSGYKRMRRQHQKQLMALENKLKAEMD------ 495

  Fly   420 GTMVELESNLGTMVINSDSDDSTTAKNND-----DQKPRNRYRPQFLEHFDRKNAGDGRGDEKPI 479
            ...:.|:..|.|...|..|:....:|.:.     :.|.......:|.:|.        .|.:|..
Zfish   496 EHQLRLDKELETQRNNFGSEADKLSKKHQAILEKETKGAIAEEKKFQQHI--------LGQQKKE 552

  Fly   480 ATEYSPAAAEQQQQQQQQQQQQQQDE--QHLASGANDLNNWEHNMEMQFQQISAINQYGLQQHQQ 542
            .|    :..|.|::..:|:::|.::|  ::.::...:...|....:...||:.|..:.||.:.|:
Zfish   553 LT----SLLESQKRHYRQRKEQLKEELNENQSTPKREKQEWLVQQKECLQQVQAEEEAGLLRRQR 613

  Fly   543 QQQVLMAYPLMNEQLIALNNQPNLLLSNAAPMGQ--QGIPAAAPAQPPPAYQNQHMHTQSHAYVE 605
            |...|.......:.|::.:|....||.......|  :.:..|       .....|..||
Zfish   614 QYYELQGRQYKRKMLLSRHNLEQDLLREDLNKKQTLKDLECA-------MLLRHHESTQ------ 665

  Fly   606 GEFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAKRKRQQ 660
             |.||.:..........|....|:.||..:.   :||.:|:..:...:|...|||
Zfish   666 -ELEFRQLALVQRTRADLIRTQHQTELTNQM---EYNKRREQELRQKHAVEVRQQ 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hpo	NP_001261092.1	STKc_MST1_2	38..293	CDD:132943	115/285 (40%)
		S_TKc	42..293	CDD:214567	112/281 (40%)
		Mst1_SARAH	608..655	CDD:288481	9/46 (20%)
taok2b	XP_009304676.1	PKc_like	6..318	CDD:304357	122/329 (37%)
		S_TKc	28..281	CDD:214567	111/258 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910