DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rep and GDI1

DIOPT Version :9

Sequence 1:	NP_477420.1	Gene:	Rep / 37246	FlyBaseID:	FBgn0026378	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_011062.1	Gene:	GDI1 / 856876	SGDID:	S000000938	Length:	451	Species:	Saccharomyces cerevisiae

Alignment Length:	461	Identity:	120/461 - (26%)
Similarity:	211/461 - (45%)	Gaps:	60/461 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDALCARLDQEVEPHS 67
            :.:...:|::|:|||.||..::...|..||.|||:|..::||...:|.::..|..:..|
Yeast     4 ETIDTDYDVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVTLSQLYEKFKQ------ 62

  Fly    68 ALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEF 132
                     :.:.||        .|:|...|.|.:::||.|:.|.|.|||..:||.:::.||.:|
Yeast    63 ---------NPISKE--------ERESKFGKDRDWNVDLIPKFLMANGELTNILIHTDVTRYVDF 110

  Fly   133 RAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFLTACNDYGEDKCN-EDSLEFRGRT 196
            :.|....:...|:|..||.:..:..::..:.|.|||.:.|||...:.|.||..: ...|:....|
Yeast   111 KQVSGSYVFKQGKIYKVPANEIEAISSPLMGIFEKRRMKKFLEWISSYKEDDLSTHQGLDLDKNT 175

  Fly   197 FLEYLQAQRVTEKISSCVMQAIAMCGPSTSFEE----GMQRTQRFLGSLGRYGNTPFLFPMYGCG 257
            ..|......:.......:..|:|:.......::    ..:|...:..|:.|||.:|:|:||||.|
Yeast   176 MDEVYYKFGLGNSTKEFIGHAMALWTNDDYLQQPARPSFERILLYCQSVARYGKSPYLYPMYGLG 240

  Fly   258 ELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEF--LLSSAGKTLRAKNVVSAPGYTPVSKGIE 320
            ||||.|.||.|:|||.|.|...:|::....::.:|  :.:..| |.:|..|::.|.|.| .|...
Yeast   241 ELPQGFARLSAIYGGTYMLDTPIDEVLYKKDTGKFEGVKTKLG-TFKAPLVIADPTYFP-EKCKS 303

  Fly   321 LKPHISRGLFISSSPLGNEELNKGGGGVNLLRLL--DNEGGREA--FLIQLSHYTGACPEGLYIF 381
            ....:.|.:.|.:.|:.|.      ...:.|:::  .::.||::  ::..:|.....|.:|.|:.
Yeast   304 TGQRVIRAICILNHPVPNT------SNADSLQIIIPQSQLGRKSDIYVAIVSDAHNVCSKGHYLA 362

  Fly   382 HLTT------PALSEDPASDLA-------IFTSQLF----DQSDAQIIFS-SYFTIAAQSSKSPA 428
            .::|      |.:..:||..|.       :..::||    |.|...|..| ||...:...|.:..
Yeast   363 IISTIIETDKPHIELEPAFKLLGPIEEKFMGIAELFEPREDGSKDNIYLSRSYDASSHFESMTDD 427

  Fly   429 AEHIYY 434
            .:.||:
Yeast   428 VKDIYF 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	NADB_Rossmann	4..397	CDD:304358	108/409 (26%)
GDI1	NP_011062.1	GDI	1..447	CDD:395792	120/461 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810