DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rep and Gdi2

DIOPT Version :9

Sequence 1:	NP_477420.1	Gene:	Rep / 37246	FlyBaseID:	FBgn0026378	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_058972.2	Gene:	Gdi2 / 29662	RGDID:	61802	Length:	445	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	125/504 - (24%)
Similarity:	215/504 - (42%)	Gaps:	115/504 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFS-MDALCARLDQEVEPHSALR 70
            |::|::|:|||.||..::...|..||.|||:|.|.|||...:|.: ::.|..|.....:|.:::.
  Rat     3 EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPASMG 67

  Fly    71 NARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEFRAV 135
            ..|               .||            :||.|:.|.|.|:||::|:.:.:.||.:|:.:
  Rat    68 RGR---------------DWN------------VDLIPKFLMANGQLVKMLLFTEVTRYMDFKVI 105

  Fly   136 DHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFL---------------------TACND 179
            :...:...|:|..||.:.::...:..:.:.|||...|||                     |:..|
  Rat   106 EGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRD 170

  Fly   180 -YGEDKCNEDSLEFRGRTFLEYLQAQRVTEKISS-CVMQAIAMCGPSTSFEEGMQRTQRFLGSLG 242
             |.:....:|.::|.|.:...|    |..:.:.. |       |       |.:.|.:.:..||.
  Rat   171 VYKKFDLGQDVIDFTGHSLALY----RTDDYLDQPC-------C-------ETINRIKLYSESLA 217

  Fly   243 RYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFLLSSAGKTLRAKNVV 307
            |||.:|:|:|:||.|||||.|.||.|:|||.|.|.:.:::|.: .|.....:.|.|:..|.|.::
  Rat   218 RYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIV-QNGKVVGVKSEGEIARCKQLI 281

  Fly   308 SAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLL--DNEGGREA----FLIQ 366
            ..|.|  |...:|....:.|.:.|.|.|:      |.....|..:::  .|:..|::    .:|.
  Rat   282 CDPSY--VKDRVEKVGQVIRVICILSHPI------KNTNDANSCQIIIPQNQVNRKSDIYVCMIS 338

  Fly   367 LSHYTGACPEGLYIFHLTTPALSEDPASDLA-------------IFTSQLFDQ----SDAQIIFS 414
            .:|...|  :|.||..::|...:::|..::.             :..|.||..    :|:||..|
  Rat   339 FAHNVAA--QGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFIS 401

  Fly   415 ------SYFTIAAQSSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGK 457
                  ::|.......|.      .|......|.|::.......||:|:
  Rat   402 RAYDATTHFETTCDDIKD------IYKRMTGSEFDFEEMKRKKNDIYGE 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	NADB_Rossmann	4..397	CDD:304358	110/419 (26%)
Gdi2	NP_058972.2	GDI	1..436	CDD:395792	122/494 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810