DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rep and Gdi1

DIOPT Version :9

Sequence 1:	NP_477420.1	Gene:	Rep / 37246	FlyBaseID:	FBgn0026378	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_034403.1	Gene:	Gdi1 / 14567	MGIID:	99846	Length:	447	Species:	Mus musculus

Alignment Length:	507	Identity:	129/507 - (25%)
Similarity:	218/507 - (42%)	Gaps:	123/507 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFS-MDALCARLD-QEVEPHS 67
            :.|::|::|:|||.||..::...|..||.|||:|.|.|||...||.: ::.|..|.. .|..|.|
Mouse     1 MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQILEGPPES 65

  Fly    68 ALRNARYTWHSMEKESETDAQSWNRDSVLAKSRRFSLDLCPRILYAAGELVQLLIKSNICRYAEF 132
                                        :.:.|.:::||.|:.|.|.|:||::|:.:.:.||.:|
Mouse    66 ----------------------------MGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDF 102

  Fly   133 RAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFL---------------------TA 176
            :.|:...:...|:|..||.:.::...:..:.:.|||...|||                     |:
Mouse   103 KVVEGSFVYKGGKIYKVPSTETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQNTS 167

  Fly   177 CND-YGEDKCNEDSLEFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFEEGMQRTQRFLGS 240
            ..| |.:....:|.::|.|.....|    |..:.:....::.|             .|.:.:..|
Mouse   168 MRDVYRKFDLGQDVIDFTGHALALY----RTDDYLDQPCLETI-------------NRIKLYSES 215

  Fly   241 LGRYGNTPFLFPMYGCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSNEFLLSSAGKTLRAKN 305
            |.|||.:|:|:|:||.|||||.|.||.|:|||.|.|.:.||||.:: |.....:.|.|:..|.|.
Mouse   216 LARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIME-NGKVVGVKSEGEVARCKQ 279

  Fly   306 VVSAPGYTPVSKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLL--DNEGGREA--FLIQ 366
            ::..|.|.|  ..::....:.|.:.|.|.|:      |.....|..:::  .|:..|::  ::..
Mouse   280 LICDPSYIP--DRVQKAGQVIRIICILSHPI------KNTNDANSCQIIIPQNQVNRKSDIYVCM 336

  Fly   367 LSHYTGACPEGLYIFHLTT------PALSEDPASDLA-------IFTSQLF----DQSDAQIIFS 414
            :|:......:|.||...:|      |....:||.:|.       :..|.|:    |.|::|:..|
Mouse   337 ISYAHNVAAQGKYIAIASTTVETAEPEKEVEPALELLEPIDQKFVAISDLYEPIDDGSESQVFCS 401

  Fly   415 -SYFTIAAQSSKSPAAEHIYYTDPPTYELDYDAAIANARDIFGKMFPDA-DF 464
             ||                   |..|:   ::....:.:||:.:|...| ||
Mouse   402 CSY-------------------DATTH---FETTCNDIKDIYKRMAGSAFDF 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	NADB_Rossmann	4..397	CDD:304358	112/425 (26%)
Gdi1	NP_034403.1	GDI	1..436	CDD:279353	129/507 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810