Protein Alignment Rep and Chm

DIOPT Version :9

• Sequence 1: NP_477420.1
• Gene: Rep / 37246
• FlyBaseID: FBgn0026378
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_061288.2
• Gene: Chm / 12662
• MGIID: 892979
• Length: 662
• Species: Mus musculus
• Alignment Length: 636
• Identity: 196/636 - (30%)
• Similarity: 295/636 - (46%)
• Gaps: 165/636 - (25%)

  Fly     1 MLDDLPEQFDLVVIGTGFTESCIAAAGSRIGKSVLHLDSNEYYGDVWSSFSMDALCARLDQEVEP 65
            |.|:||..||::|||||..||.||||.||.|:.|||:||..|||..|:|||...|.:.| :|.:.
Mouse     1 MADNLPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGLLSWL-KEYQE 64

  Fly    66 HSALRNARYTWHSM--------------------------------------------------- 79
            :|.:......|...
Mouse    65 NSDVVTENSMWQEQILENEEAILLSSKDKTIQHVEVFCYASQDLHKDVEEAGALQKNPASVMSAQ 129

  Fly    80 -------------------------------------------------------------EKES 83
                                                                         |||:
Mouse   130 ATEAAEAAEAAEAAEATEAAEAACLPTAEESLSTRSCELPAEQSQCTGPESSPQVNDAEVGEKET 194

  Fly    84 ETDAQSWNRDS-----------------------VLAKSRRFSLDLCPRILYAAGELVQLLIKSN 125
            ::||:|....|                       ::.:.|||::||..::||:.|.|:.||||||
Mouse   195 QSDAKSSTEQSSEILPKVQDNTETPKRNVITYSQIIKEGRRFNIDLVSKLLYSRGLLIDLLIKSN 259

  Fly   126 ICRYAEFRAVDHVCMRHNGEIVSVPCSRSDVFNTKTLTIVEKRLLMKFLTACNDYGEDKCNEDSL 190
            :.|||||:.:..:.....|.:..|||||:||||:|.||:||||:||||||.|.:| ||..:|..
Mouse   260 VSRYAEFKNITRILAFREGTVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCVEY-EDHPDEYK- 322

  Fly   191 EFRGRTFLEYLQAQRVTEKISSCVMQAIAMCGPSTSFE-EGMQRTQRFLGSLGRYGNTPFLFPMY 254
            .:...||.|||:.|::|..:...|:.:|||...:||.. :|::.|::||..||||||||||||:|
Mouse   323 AYEETTFSEYLKTQKLTPNLQYFVLHSIAMTSETTSSTVDGLKATKKFLQCLGRYGNTPFLFPLY 387

  Fly   255 GCGELPQCFCRLCAVYGGIYCLKRAVDDIALDSNSN--EFLLSSAGKTLRAKNVVSAPGYTP--V 315
            |.|||||||||:|||:||||||:.:|..:.:|..|.  :.::...|:.:.:|:.|....|..  .
Mouse   388 GQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAIVDQFGQRIISKHFVIEDSYLSENT 452

  Fly   316 SKGIELKPHISRGLFISSSPLGNEELNKGGGGVNLLRLLDNEGGREAF-LIQLSHYTGACPEGLY 379
            ..|::.: .|||.:.|:...:...:.::   .|::|.:...|.|..|. :|:|...|..|.:|.|
Mouse   453 CSGVQYR-QISRAVLITDGSVLKPDSDQ---QVSILTVPAEESGSFAVRVIELCSSTMTCMKGTY 513

  Fly   380 IFHLTTPALSEDPASDLAIFTSQLF----------DQSD-AQIIFSSYFTIAAQSSKS-----PA 428
            :.|||..: |:....||.....:||          :|.: .:|:::.||.:...|..|     ..
Mouse   514 LVHLTCMS-SKTAREDLERVVQKLFTPYTEIEAENEQVEKPRILWALYFNMRDSSDISRDCYNDL 577

  Fly   429 AEHIYYTDPPTYELDYDAAIANARDIFGKMFPDADFLPRAPDPEEIVVDGE 479
            ..::|....|...|..|.|:..|..:|.|:.|:.||.|..|:||:|::||:
Mouse   578 PSNVYVCSGPDCNLGNDNAVQQAETVFQKICPNEDFCPAPPNPEDIILDGD 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rep	NP_477420.1	NADB_Rossmann	4..397	CDD:304358	167/533 (31%)
Chm	NP_061288.2	GLF	8..>46	CDD:391719	24/37 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	164..216		7/51 (14%)
		NADB_Rossmann	234..542	CDD:389744	128/314 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	617..662		6/12 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841035
Domainoid	1	1.000	219	1.000	Domainoid score	I2628
eggNOG	1	0.900	-	-		E1_COG5044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H334
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3186
Isobase	1	0.950	-	0.811278	Normalized mean entropy	S3491
OMA	1	1.010	-	-		QHG54506
OrthoDB	1	1.010	-	-		D1017439at2759
OrthoFinder	1	1.000	-	-		FOG0004306
OrthoInspector	1	1.000	-	-		otm43642
orthoMCL	1	0.900	-	-		OOG6_103227
Panther	1	1.100	-	-	LDO	PTHR11787
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1844
SonicParanoid	1	1.000	-	-		X3039
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750