Protein Alignment Oseg6 and Oseg6

DIOPT Version :10

• Sequence 1: NP_611426.1
• Gene: Oseg6 / 37245
• FlyBaseID: FBgn0034452
• Length: 1366
• Species: Drosophila melanogaster
• Sequence 2: XP_061512486.1
• Gene: Oseg6 / 3291083
• VectorBaseID: AGAMI1_006396
• Length: 1360
• Species: Anopheles gambiae
• Alignment Length: 1371
• Identity: 754/1371 - (54%)
• Similarity: 1021/1371 - (74%)
• Gaps: 16/1371 - (1%)

  Fly     1 MSFEKILYKYEEPHGIGDVYFIWQKA----LLATTGTDGSVALYNRQGQLVQRIILSGLCSGFAW 61
            ||.||:||::|||||.|||||:||..    |||:||:||:||:|||||||.:||:|.|||:||||
Mosquito     1 MSSEKVLYRHEEPHGQGDVYFLWQTGASAQLLASTGSDGTVAIYNRQGQLQERIVLQGLCAGFAW 65

  Fly    62 DQEGDLLGIITSGSPNITLWDYNSQEKISVETGLRDPLTCILWSKQQQLLAVGTGRGNLAIYNHS 126
            |::||:|.:||:.|..:.:||.|||:|.:|:.||||..:||:|||:..:|||||.||||:||||.
Mosquito    66 DRDGDVLAMITASSHQLIIWDSNSQKKQTVDIGLRDLPSCIIWSKKIAILAVGTARGNLSIYNHI 130

  Fly   127 SGKRPTPVLGKHSKRITCGAWSAQNLLALGSEDKSFSLSNEDGDTVRVVQLRDAPTDMYFAEMAN 191
            |.|| .|:||||:|||||||||.:|:||||||||..:||||:|||:|.:||||.|:|||||||..
Mosquito   131 STKR-IPILGKHTKRITCGAWSTENILALGSEDKYLTLSNEEGDTLRSIQLRDCPSDMYFAEMKT 194

  Fly   192 DERIAGDNAISMIIGKRTLFLYYLPEPENPTELGFQSRYGSLMQHKWFGDGYILLGFSNGHVVAI 256
            |||:.|:|.||||:||||||||:||||::|||||||.|||||:|||||.|||||||||.||||||
Mosquito   195 DERVPGENTISMILGKRTLFLYHLPEPDSPTELGFQQRYGSLLQHKWFADGYILLGFSLGHVVAI 259

  Fly   257 STHPKDVGQELWQVKNHKDSLTGLAYCPTLDIVASCGDDSIKIHSITNLQETERIITVPDHAGVQ 321
            ||||::|||||||||||:|||..:|.|..|:::|||||:::||||:||||||.:|:::||.|.::
Mosquito   260 STHPREVGQELWQVKNHRDSLNSIAVCKELELIASCGDNNVKIHSMTNLQETVKILSLPDQAALK 324

  Fly   322 MIDWSPDGQLLAVTTNHGTVYIYVTKLPHLFAVSAPRIVLLSSLAEVSIYVYAPDKTKSLPFRLP 386
            .::||.|||||.|||:.|.:.::||||..|:||:.|||.|||||||::||.|.||:.||.|..:.
Mosquito   325 HVEWSADGQLLGVTTSQGAICVFVTKLHSLYAVAPPRIALLSSLAEIAIYHYTPDRQKSPPVLIT 389

  Fly   387 LEGEPTFMAVGPYNFATGIEKHVWFYDLGKSLGEEPRPLSERDFPRSVESMKLNADYCAALCPPQ 451
            ||.||:|:.:|||:.|.|:..||||||||:|:.:.|..|.:|::...::.:.|:::|||.||..|
Mosquito   390 LEIEPSFLTIGPYHMACGMNNHVWFYDLGRSMTDTPLLLGDREYMSEIKQVALSSEYCAVLCGGQ 454

  Fly   452 LILQAIAADNPNCKDKLQAVFPTALPNMPSDAVITCFALSQELLIFATDIGHLVFYSLEKWDSCT 516
            ::|..|.:.....:::...:||..:..: :::||||..|:.:.|.||||:|:::::|||.|.:..
Mosquito   455 IMLHTIESSTETSQNREPKIFPDEIRGI-AESVITCLGLTNDFLCFATDLGNIIYFSLENWSTVL 518

  Fly   517 IYRHSMGIRQLFMDIEGTKVIFIDDHSQGYVFLPVVEEALLIPDIPKQCLGCLWDLTQPNIFISY 581
            .:||..|||.::.|::.|:::|||||||||:|:...:|.|.|||.||.|.|.|||.:||:||::.
Mosquito   519 QFRHQAGIRAIYPDVDATRLVFIDDHSQGYLFIAACDETLRIPDFPKHCPGVLWDYSQPHIFVAN 583

  Fly   582 DARIVNTHVFVRHSVQGTHTLMVGESKLNPGQFPLLLCGGEMALHIDGGQYATQSLSTHVVNPSN 646
            |.....|:.|||.||:|.....||.:.|...|.||:|..|::.||..||:..:..|.||...|..
Mosquito   584 DRNTCTTYAFVRVSVKGKMVEKVGTTSLISEQTPLMLYDGDLCLHGSGGKLTSIVLDTHANKPGR 648

  Fly   647 SQAANLQMLLKLRNYDEAYKLCKQMNQSSAWREFGEQAISDLEPDIAIRAYRQLGDAALVNALSE 711
            .....|:....:|.|.:|::|||.||....|||.|..||:||....|::.:|.:||.|:|.||.:
Mosquito   649 DVKEQLRTTKLMRKYPDAWELCKLMNDIDEWRELGMAAIADLNISFAMKVFRNIGDVAMVYALED 713

  Fly   712 LRYVEDLDMLIGCCCTLLAQYDQAKEHMLKGVYTRAALDLCRDLLQWDQALLLAHKNDPQEVPYI 776
            |..:|||:.|.|.|..|..:.::||....|......||:||||||||:||:.||....|:::|::
Mosquito   714 LSQIEDLNTLAGFCAVLRNEIEEAKTLFAKSGNPSEALELCRDLLQWEQAMALASTLAPEQLPFL 778

  Fly   777 AREYAQQLEFNGNYTDALYHYEKGYKEDLINSKETETDALMDSSPEYEEHVRLCKMGIARTSIRA 841
            ||||..||||.||:.:||.::|:|.       |.|||.:......:||:||:|||.|||||||:.
Mosquito   779 AREYGAQLEFTGNHAEALMNFERGL-------KHTETGSPESKQQQYEQHVKLCKAGIARTSIKC 836

  Fly   842 GDFRRGIQYAVELEDQQLLFDCAELLATVGHLTEAAGLYERGGFYDEACGHYIALKMWNKANNIL 906
            ||.|||:|.|:||.|:||..||.|.:...||:.|||.:.|||..:|:|...:|.||.|.|.:|||
Mosquito   837 GDVRRGLQLALELNDKQLYNDCGEAMVAAGHMAEAASMLERGENWDKAAEIFINLKQWKKVDNIL 901

  Fly   907 PKVKSTKLHAAYAKAKENDGHYEEAIRSYRIAGDLDACVRIYLDHLCDPHAASEIVLESRSMDSA 971
            |.|.|.||||||.||||.:|||.:||.||::|||||..|||||.||.|||:||||:||:||::.:
Mosquito   902 PNVVSLKLHAAYGKAKEAEGHYADAINSYQLAGDLDGVVRIYLQHLDDPHSASEILLETRSVEGS 966

  Fly   972 KLLAKFYQKIGDVEQALQFLVICGCVEEAFALAQRHNKLRRHGELLERYENAKSSDYLALAHYFE 1036
            |:|:|::::.||.|.|:|||::|||:.|||::||:.||:..:||:||:...||..|:|.|..:|:
Mosquito   967 KMLSKYFEQHGDYESAIQFLILCGCITEAFSIAQKQNKIVYYGEVLEQSAAAKPGDFLQLGGHFD 1031

  Fly  1037 GEKYTLLAGKYYFLAREFTKALRFLLKASAFNNEEQVSLSLAIDCVATSNNEQLATQLIEFLLGE 1101
            .|||||||||||||.:|::|||:.||||::..|||..:|||||||||::.:|:|:..|||:||||
Mosquito  1032 TEKYTLLAGKYYFLGKEYSKALKLLLKAASVGNEENTALSLAIDCVASAGDEKLSNVLIEYLLGE 1096

  Fly  1102 VDGVPKDPRYLFRLYMARKHYKDAAKTAVIIANQEQIAGNYKSARDLLYSMYQELRRNNLSVTAE 1166
            .|||||||:.|||||||::.:|:|||.|:||||||||||||:||.|||:||||||:||:|::..:
Mosquito  1097 SDGVPKDPKLLFRLYMAKRQFKEAAKAAMIIANQEQIAGNYRSAHDLLFSMYQELKRNHLAIATD 1161

  Fly  1167 MRHQFILLHRYTLVRIHVKLGNHLLAAKLLVQVAACISQFPEHIIPILTSTVIECHRAGLKKSAF 1231
            |:....|||||||||||||.||||||||||:|||..|||||.|::||||||||||||.||:||||
Mosquito  1162 MKTTLGLLHRYTLVRIHVKRGNHLLAAKLLLQVANNISQFPSHVVPILTSTVIECHRTGLRKSAF 1226

  Fly  1232 TYASTLMRPDYRNQLDPRYAKKIESIVRKAPKGIKQLRDEIDGETMECPICDSNLANMEVTCYSC 1296
            .||..|||.::|:.:|.:|.|||||||||||:|  |:.|:.:.|:..||:|::.|.||.:.|..|
Mosquito  1227 EYAVMLMRSEHRSHIDSKYIKKIESIVRKAPRG--QMEDDGEQESSPCPVCETPLPNMHIVCGQC 1289

  Fly  1297 KTTLPICIATGQHIIKQLMTSCPQCDFLCFRAEMENIL-SENGECPMCGENVAPEQLLDVEDIRP 1360
            ||||||||||||||::..:.:||:|||...:.|...|| :.|.:|.||||.:...:|:|::||:.
Mosquito  1290 KTTLPICIATGQHIVRDEVAACPECDFPAMKVEFIKILETTNNQCAMCGEEIDAGRLVDIDDIQH 1354

  Fly  1361 YILAAS 1366
            ||.|.:
Mosquito  1355 YINAGT 1360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oseg6	NP_611426.1	WD40 repeat	16..49	CDD:293791	23/36 (64%)
		WD40	<26..344	CDD:441893	212/321 (66%)
		WD40 repeat	56..97	CDD:293791	21/40 (53%)
		WD40 repeat	100..137	CDD:293791	23/36 (64%)
		WD40 repeat	142..176	CDD:293791	24/33 (73%)
		WD40 repeat	185..225	CDD:293791	29/39 (74%)
		WD40 repeat	232..271	CDD:293791	33/38 (87%)
		WD40 repeat	277..313	CDD:293791	20/35 (57%)
		WD40 repeat	320..344	CDD:293791	11/23 (48%)
		WD40_3	515..571	CDD:464937	27/55 (49%)
		LapB	731..1024	CDD:442196	151/292 (52%)
Oseg6	XP_061512486.1	None