Protein Alignment CG7744 and Tmem201

DIOPT Version :10

• Sequence 1: NP_611422.2
• Gene: CG7744 / 37239
• FlyBaseID: FBgn0034447
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001418231.1
• Gene: Tmem201 / 691426
• RGDID: 1583947
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 747
• Identity: 162/747 - (21%)
• Similarity: 258/747 - (34%)
• Gaps: 288/747 - (38%)

  Fly    13 IPVCAILFVAGTFLFKVYISIRSRYDARVNCWFCNGNVRVPYQDRNSWTCPSCEQYNGFTKDGDY 77
            :..||   .||..|:::...::..: ..|||||||.:..|||.:||.|.||.|||||||.::|||
  Rat    22 VTACA---AAGVVLYRIARRVKPTH-TMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDY 82

  Fly    78 NRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPA-PKNG------LCDQCNEAQRLKV 135
            |:.|.:|....|               |...|.|.:.:.|| |:..      ||.:|:..|..|:
  Rat    83 NKPIPAQYMEHL---------------NHVVSSVPSPRDPAQPQQWVSSQVLLCRKCSHHQTTKI 132

  Fly   136 EKLSQFEPKNESRFDQELKVYRERLEKQFRLCSSCE-------RHVNKVLHEKKKMVLSSKFLNY 193
            ::|:.|.|:.|.|:|:|::|||..||:.::||..|:       :|.|:.|   :.::||.:|...
  Rat   133 KQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVDYYIKHQNRQL---RALLLSHQFRRR 194

  Fly   194 IIKGA-------SLLKQPHFNRLAAAQKQFKLQRYRILMTILTVVNILCLL-------------- 237
            .:..|       |.:|.|           |::    ||:..|..:....||
  Rat   195 EVDQAHGQSFSSSAMKAP-----------FQV----ILLRALAFLACAFLLSTALYGPGEPFTPG 244

  Fly   238 CRLP--------------NATS-----IQFTTYLGKFIGLTLFYAY----SHVLALIRV--VTSS 277
            ..||              ||||     .|....|.:.....|..|:    ||...::.|  :|..
  Rat   245 AALPPALPPGGNSSAASDNATSQAEGWQQLLGLLPEHATEKLHEAWAFGQSHQTGIVAVGLLTCL 309

  Fly   278 VGIFLEQREMIAKLLLYGRTFGKLLLYSLGIGQQQVQQATFASCFIGIYPYAMLALCFLHTIYDG 342
            :.:.|..|..:.::..:......||| .|.:.:..:|.|  :..::....::..:||.|
  Rat   310 LAMLLAGRIRLRRIDAFSTCLWALLL-GLHLAEHYLQAA--SPGWLDTLKFSTTSLCCL------ 365

  Fly   343 LKFTRFTIALLLWSGYAMGIEFLDP--YISGISFILVGSFVTLVLLATNRTNLLSQVNRDESACE 405
               ..||.|:.  :..|.|.....|  |.||.|..|.
  Rat   366 ---VGFTAAVA--TRKATGPRRFRPRRYFSGDSASLF---------------------------- 397

  Fly   406 SFHRLCADECDDETLSMLSQQLSGYSDISNSNLSMRTASVCHSPAPTISQRTIQAPASLLSLDSL 470
                                       :|:.:|::...||..|||...    |..|...|.
  Rat   398 ---------------------------LSSPSLAVPYPSVTASPASLF----IPTPPGFLP---- 427

  Fly   471 HLSKQRMEQQAWSSNYGDASTVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQN 535
             ||||::.:              :||
  Rat   428 -LSKQQLFR--------------SPR--------------------------------------- 438

  Fly   536 LLMPSRLPS-INRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQP 599
            .:.||.||. ::|.:....:.:                            |:||.|......|:|
  Rat   439 RVSPSSLPGRLSRALSLGTIPS----------------------------LTRTDSGYLFSGSRP 475

  Fly   600 RPEAQCGTGAATVRDYGWSEARESQRNFAV----FP--PMPSPTPTITPSEYQYSRTALPQQQPT 658
             |......|..::.||           |::    ||  |:|||.|::. |....|..:|..::|.
  Rat   476 -PSRVSPAGEVSLSDY-----------FSLLSSSFPSSPLPSPAPSVA-SSVASSSGSLRHRRPL 527

  Fly   659 MQPGDLLRKWIEI----------NSKSSQPIH 680
            :.|..|..|..::          |:.||...|
  Rat   528 ISPARLNLKGQKLLLFSPPGEAPNTPSSSEEH 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7744	NP_611422.2	Ima1_N	42..172	CDD:462895	54/143 (38%)
Tmem201	NP_001418231.1	Ima1_N	47..169	CDD:462895	54/136 (40%)
		DUF2448	191..379	CDD:463104	40/216 (19%)