Protein Alignment CG7744 and tmem201

DIOPT Version :10

• Sequence 1: NP_611422.2
• Gene: CG7744 / 37239
• FlyBaseID: FBgn0034447
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_009295126.1
• Gene: tmem201 / 563814
• ZFINID: ZDB-GENE-070410-61
• Length: 664
• Species: Danio rerio
• Alignment Length: 762
• Identity: 163/762 - (21%)
• Similarity: 255/762 - (33%)
• Gaps: 308/762 - (40%)

  Fly     8 LAATAIPVCAILFVAGTFLFKVYISIRSRYDARVNCWFCNGNVRVPYQDRNSWTCPSCEQYNGFT 72
            :.|||:.      ..|..::::....:..: .:|||||||.:..|||.:||.|.||.|||||||.
Zfish    19 VGATAVA------AGGALIYRIATRKKPTH-LQVNCWFCNQDTVVPYGNRNCWDCPYCEQYNGFQ 76

  Fly    73 KDGDYNRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPAPKN--------GLCDQCNE 129
            ::||||:.|.:|      ..::.:.|.|:            ..|..||.        .||.:||.
Zfish    77 ENGDYNKPIPAQ------YMEHLNHGVSA------------GVPETPKTLQWVNCQMLLCKKCNN 123

  Fly   130 AQRLKVEKLSQFEPKNESRFDQELKVYRERLEKQFRLCSSCERHVN-KVLHEKKKMVLSSKFLNY 193
            .|.||:::|:.|.|:.:..:|:|::||:..||:.::||..|:..|. .:.|:.:::
Zfish   124 NQTLKIKQLASFIPREDENYDEEIEVYKHHLEQTYKLCRPCQTAVEYYIKHQNRQL--------- 179

  Fly   194 IIKGASLLKQPHFNRLAAAQKQFKLQRYR-------ILMTILTVVNILCLLCRLPNATSIQFTTY 251
                .:||......|...|.|.|....|.       ||:.|||.     |.|..  ..::..:.|
Zfish   180 ----RALLFNHQLRRTRDADKAFIKNTYSLSTPAWLILLRILTF-----LACAF--LVAVALSGY 233

  Fly   252 LGKFIGLTLFYAYSHVLALIRVVTSSVGIF----LEQREMIAKL----LLYGRTFGKL------- 301
            :.:...:|              .|.|.|:.    :.|.|..:|.    |::....|.|
Zfish   234 VDESPSVT--------------QTLSGGVVPPKRVLQNENESKTDEGSLMWDDLMGLLPEKAVEN 284

  Fly   302 --LLYSLGIGQQQ-VQQATFASCFIGIY---PYAM------------------LALCFLHT-IYD 341
              |.:..|...|. |......:|..|:.   |..:                  ||.|:|.| :..
Zfish   285 ARLFWQSGSDHQMAVASVGLLTCITGVLMAGPVRLRRIDAVASVLWLLVICFYLAECYLKTDVPS 349

  Fly   342 GLKFTRFTI-ALLLWSGYAMGIEFLDP----------YISGISFILVGSFVTLVLLATNRTNLLS 395
            .|:..:|.| ::....|:|..:.....          |:||.|   .|.|.      .|...|||
Zfish   350 WLEMVKFGITSVCCLVGFAAAVATRKSTSQRRARGRRYLSGGS---PGEFF------CNHGPLLS 405

  Fly   396 QVNRDESACESFHRLCADECDDETLSMLSQQLSGYSDISNSNLSMRTASVCHSPAPTISQRTIQA 460
                                               :.:|.|:..:.|      |.|.:||
Zfish   406 -----------------------------------APVSESSTFIPT------PPPNLSQ----- 424

  Fly   461 PASLLSLDSLHLSKQRMEQQAWSSNYGDASTVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQ 525
                                                    ::.:|:..|
Zfish   425 ----------------------------------------LLIRQQSQR---------------- 433

  Fly   526 GNTFTRSTQNLLMPSRLPS-INRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTS 589
                ||...    ||.||. :||.:....:.:                            |:||
Zfish   434 ----TRKAS----PSSLPGRLNRALSLGTIPS----------------------------LART- 461

  Fly   590 SQSSGF-ESQPRPEAQCGTGAATVR-----------DYG--WSEARESQRNFAVFPPMPSPTPTI 640
              .||| .|..||.:||.....:|.           ||.  .|.:|.|.       |.|||||::
Zfish   462 --DSGFLFSGSRPSSQCKDSPPSVTSADVTFCCFSLDYYSLKSGSRPSS-------PGPSPTPSV 517

  Fly   641 TPSEYQYSRTALPQQQPTMQP------GDLLRKW---IEINSKSSQP 678
            ..|....|.:| .|::|.:.|      |..||.:   :|..|.:|.|
Zfish   518 AGSVTSTSSSA-RQRRPLISPARLNISGQKLRLFSSPLEPFSLASPP 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7744	NP_611422.2	Ima1_N	42..172	CDD:462895	51/137 (37%)
tmem201	XP_009295126.1	Ima1_N	46..165	CDD:462895	50/136 (37%)
		DUF2448	188..388	CDD:463104	40/220 (18%)