Protein Alignment CG7744 and Tmem201

DIOPT Version :10

• Sequence 1: NP_611422.2
• Gene: CG7744 / 37239
• FlyBaseID: FBgn0034447
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001271199.1
• Gene: Tmem201 / 230917
• MGIID: 1196277
• Length: 664
• Species: Mus musculus
• Alignment Length: 714
• Identity: 153/714 - (21%)
• Similarity: 255/714 - (35%)
• Gaps: 216/714 - (30%)

  Fly    13 IPVCAILFVAGTFLFKVYISIRSRYDARVNCWFCNGNVRVPYQDRNSWTCPSCEQYNGFTKDGDY 77
            :..||   .||..|:::...::..: ..|||||||.:..|||.:||.|.||.|||||||.::|||
Mouse    22 VTACA---AAGVVLYRIARRVKPTH-TMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDY 82

  Fly    78 NRDITSQRDCSLGSQKNSSKGSSSICANSYYSDVLTAQPPA-PKNG------LCDQCNEAQRLKV 135
            |:.|.:|....|               |...|.|.:.:.|| |:..      ||.:|:..|..|:
Mouse    83 NKPIPAQYMEHL---------------NHVVSSVPSPRDPAQPQQWVSSQVLLCRRCSHHQTTKI 132

  Fly   136 EKLSQFEPKNESRFDQELKVYRERLEKQFRLCSSCERHVN-KVLHEKKKMVLSSKFLNYIIKGAS 199
            ::|:.|.|:.|.|:|:|::|||..||:.::||..|:..|. .:.|:.:::             .:
Mouse   133 KQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQL-------------RA 184

  Fly   200 LLKQPHFNRLAAAQ---KQFKLQRYRILMTILTVVNILCLLCRLPNATSIQFTTYLG-------- 253
            ||....|.|..|.|   :.|.....:....::.:..:..|.|..     :.|||..|
Mouse   185 LLLSHQFRRREADQAHGQSFSSSAVKAPFQVILLRALAFLACAF-----LLFTTLYGPSEPFTPG 244

  Fly   254 ----------------------------KFIGL-----------TLFYAYSHVLALIRV--VTSS 277
                                        :.:||           ...:..||..:::.|  :|..
Mouse   245 AALPPALPPGGNSSAASDNTTSQAEGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCL 309

  Fly   278 VGIFLEQREMIAKLLLYGRTFGKLLLYSLGIGQQQVQQATFASCFIGIYPYAMLALCFLHTIYDG 342
            :.:.|..|..:.::..:......||| .|.:.:..:|.|  :..::....::..:||.|
Mouse   310 LAMLLAGRIRLRRIDAFSTCLWALLL-GLHLAEHYLQAA--SPGWLDTLKFSTTSLCCL------ 365

  Fly   343 LKFTRFTIALLLWSGYAMGIEFLDP--YISGISFILVGSFVTLVL-------------------- 385
               ..||.|:.  :..:.|.....|  |.||.|..|..|..:|.:
Mouse   366 ---VGFTAAVA--TRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPPGF 425

  Fly   386 LATNRTNLLSQVNRDESACESFHRLCADECDDETLSMLSQQLSGY-------------------S 431
            |...:..|.....|...:  |.....:......|:..|::..|||                   |
Mouse   426 LPLTKQQLFRSPRRVSPS--SLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLS 488

  Fly   432 DISNSNLSMRTASVCHSPAPTISQRTIQAPAS------LLSLDSLHLSKQRMEQQAWSSNYGDAS 490
            |..:...|...||...||||:::.....:..|      |:|...|:|..|::   ...|:.|:|
Mouse   489 DYFSLLSSSFPASPLPSPAPSVASSVASSSGSLRHRRPLISPARLNLKGQKL---LLFSSPGEA- 549

  Fly   491 TVVAPRVQPAMMFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQNLLMPSRLPSINRNVGGADVS 555
                            |..|..|:     :.:...|:.|..|.|   :|.|
Mouse   550 ----------------PNTPSSSE-----EFSPPNGSLFIESPQ---LPQR-------------- 576

  Fly   556 AWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQPRPEAQCGTGAATVRDYGWSE 619
                     |....|.:.|     :.::.|:|.|::||....:....:|..|........|.||
Mouse   577 ---------NHTRDTKHTM-----EMRSMLARDSARSSHSIKKEDESSQSSTCVVDTTTKGCSE 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7744	NP_611422.2	Ima1_N	42..172	CDD:462895	54/136 (40%)
Tmem201	NP_001271199.1	Ima1_N	47..169	CDD:462895	54/136 (40%)
		DUF2448	191..379	CDD:463104	31/206 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..264		0/18 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..522		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	544..629		25/136 (18%)