Protein Alignment betaTub56D and TUB3

DIOPT Version :10

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_013582.1
• Gene: TUB3 / 854915
• SGDID: S000004593
• Length: 445
• Species: Saccharomyces cerevisiae
• Alignment Length: 428
• Identity: 175/428 - (40%)
• Similarity: 261/428 - (60%)
• Gaps: 18/428 - (4%)

  Fly    30 WEIISDEHGIDATGAYHGDSDLQL-----ERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGP 89
            ||:.|.||||...|  |.:..|..     |..:.:::|...||:||||:.|||||..:|.||:|.
Yeast    21 WELYSLEHGIKEDG--HLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGR 83

  Fly    90 FGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGS 154
            |.::|.|:..:.|:..|.||:|:||||.|.|:||.|.:.:||.|:.||.||||..||||||||||
Yeast    84 FKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGS 148

  Fly   155 GMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 219
            |:|:||:..:..||..:....::|.|:|::|.:||||||..|:.|..:|:.|.|:.:||||:|||
Yeast   149 GLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDI 213

  Fly   220 CFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTS 284
            |.|.|.::.|::.:||.|::..:|.||..|||.|.||.||.:...|:||:||:||.:..:||:.|
Yeast   214 CKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILS 278

  Fly   285 RGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSY 349
            :....:.:.:|.|:|...|:..|.|..|||..|:|:....::||.:..::|...:..::||.:..
Yeast   279 KKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQ 343

  Fly   350 FVEWIPNNVKTAVCDIPPRGLKMS--------ATFIGNSTAIQELFKRISEQFTAMFRRKAFLHW 406
            .|:|.|...|..:|..||..:..|        ...:.|:|||.:.:|||.::|..|:.::||:||
Yeast   344 MVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHW 408

  Fly   407 YTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAE 444
            |.||||:|.|||||.   .||.:..:.|.|..||..||
Yeast   409 YVGEGMEEGEFTEAR---EDLAALERDYIEVGADSYAE 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	171/420 (41%)
TUB3	NP_013582.1	alpha_tubulin	2..436	CDD:276955	170/419 (41%)