Protein Alignment betaTub56D and TUB4

DIOPT Version :10

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_013313.1
• Gene: TUB4 / 850909
• SGDID: S000004202
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 469
• Identity: 127/469 - (27%)
• Similarity: 215/469 - (45%)
• Gaps: 65/469 - (13%)

  Fly    30 WEIISDEHGIDATG-------AYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRS 87
            |..::.||.|...|       :...|.|.:     .::.|.|..|:.|||:::|.||..:..|.:
Yeast    22 WSQLAKEHAIGTDGLSQLPDSSTERDDDTK-----PFFRENSRNKFTPRAIMMDSEPSVIADVEN 81

  Fly    88 GPFGQIFRPDNFVFGQSG--AGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGG 150
             .|...|.|.|......|  |||:||.| |..|....|.:|:.:.||.:|.|..:||||.||:.|
Yeast    82 -TFRGFFDPRNTWVASDGASAGNSWANG-YDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAG 144

  Fly   151 GTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEA 215
            |||||:|:.|:..:.:.||.:|:.||||.|: :.|:.||:.||..|::.:|:|::|.|...||.:
Yeast   145 GTGSGLGSNLLEALCDRYPKKILTTYSVFPA-RSSEVVVQSYNTILALRRLIEDSDATVVFDNAS 208

  Fly   216 LYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFA 280
            |.:|..:..:.........|.|:|..:|.||..:|||..:.:.:..:...::|.|.|||..|.|.
Yeast   209 LLNISGKVFRNPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFT 273

  Fly   281 PLTS---------RGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVD 336
            |.||         :|...|      ::...:.|..|.:.:....:..|..|.....|.:..:::.
Yeast   274 PFTSDYIHDDIAHKGHSSY------DVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQIS 332

  Fly   337 EQMLNIQNKNSSYFVEWIPN----NV--KTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFT 395
            ..|..:|.:..  |..|..:    |:  ::....:.|...::|...:.|.:.:..:|:.....|.
Yeast   333 RAMTKLQQRIK--FPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFD 395

  Fly   396 AMFRRKAFLHWY-TGEGMDEM-----EFTEAESNMNDLVSEYQQYQEATADEDA----------- 443
            .:|.:.|||:.| .|:....|     ||.|:...:..|:.:|     ..|::|:
Yeast   396 KVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDY-----VAAEQDSYLDDVLVDDEN 455

  Fly   444 ---EFEEEQEAEVD 454
               |.||:.:|:.|
Yeast   456 MVGELEEDLDADGD 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	120/437 (27%)
TUB4	NP_013313.1	gamma_tubulin	3..437	CDD:276957	119/430 (28%)