Protein Alignment betaTub56D and TUBA1C

DIOPT Version :9

• Sequence 1: NP_725896.1
• Gene: betaTub56D / 37238
• FlyBaseID: FBgn0284243
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001290043.1
• Gene: TUBA1C / 84790
• HGNCID: 20768
• Length: 519
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 173/428 - (40%)
• Similarity: 260/428 - (60%)
• Gaps: 10/428 - (2%)

  Fly    30 WEIISDEHGIDATGAYHGDSDL--QLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQ 92
            ||:...||||...|....|..:  ..:..|.:::|...||:|||||.|||||..:|.||:|.:.|
Human    91 WELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQ 155

  Fly    93 IFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMG 157
            :|.|:..:.|:..|.||:|:||||.|.|::|.|||.:||.|:.|..||||.:.||.|||||||..
Human   156 LFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFT 220

  Fly   158 TLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR 222
            :||:.::..:|..:....:|:.|:|:||..||||||:.|:.|..:|::|..:.:||||:||||.|
Human   221 SLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRR 285

  Fly   223 TLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 287
            .|.:..|||.:||.|:|..:|.:|..|||.|.||.||.:...|:||:||:||.:..:||:.|...
Human   286 NLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEK 350

  Fly   288 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVE 352
            ..:..|||.|:|...|:..|.|..||||||:|:....::||.:..|:|:..:..|:.|.:..||:
Human   351 AYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVD 415

  Fly   353 WIPNNVKTAVCDIPP--------RGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG 409
            |.|...|..:...||        ..::.:...:.|:||:.|.:.|:..:|..|:.::||:|||.|
Human   416 WCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVG 480

  Fly   410 EGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAEFEE 447
            |||:|.||:||..:|..|..:|::....:||.:.|.||
Human   481 EGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	168/414 (41%)
		PLN00220	29..438	CDD:215107	168/417 (40%)
TUBA1C	NP_001290043.1	PTZ00335	72..518	CDD:185562	171/426 (40%)
		alpha_tubulin	72..505	CDD:276955	168/413 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810