DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment betaTub56D and TUB1

DIOPT Version :9

Sequence 1:	NP_725896.1	Gene:	betaTub56D / 37238	FlyBaseID:	FBgn0284243	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_177706.1	Gene:	TUB1 / 843911	AraportID:	AT1G75780	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	358/423 - (84%)
Similarity:	401/423 - (94%)	Gaps:	1/423 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FWEIISDEHGIDATGAYHGDS-DLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQ 92
            |||:|.||||:|.||.|:||| |||||||||||||||||:|||||||:|||||||||:||||:||
plant    20 FWEVICDEHGVDPTGRYNGDSADLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSIRSGPYGQ 84

  Fly    93 IFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMG 157
            |||||||||||||||||||||||||||||:|:||||||||||:||||||||:.||||||||||||
plant    85 IFRPDNFVFGQSGAGNNWAKGHYTEGAELIDAVLDVVRKEAENCDCLQGFQVCHSLGGGTGSGMG 149

  Fly   158 TLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFR 222
            ||||||||||||||:|.|:||.|||||||||||||||||||||||||.||...:|||||||||||
plant   150 TLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADECMVLDNEALYDICFR 214

  Fly   223 TLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGS 287
            ||||:||::||||||:|.||||||..||||||||:||||||||::|||||||||.||||||||||
plant   215 TLKLSTPSFGDLNHLISATMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGS 279

  Fly   288 QQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVE 352
            |||.:||||||||||:||||||.|.|||||||||.:|:|||:||.||||||:||:||||||||||
plant   280 QQYISLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGKMSTKEVDEQILNVQNKNSSYFVE 344

  Fly   353 WIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF 417
            |||||||::||||||.|:||::||:||||:|||:|:|:|||||||||||||||||||||||||||
plant   345 WIPNNVKSSVCDIPPTGIKMASTFVGNSTSIQEMFRRVSEQFTAMFRRKAFLHWYTGEGMDEMEF 409

  Fly   418 TEAESNMNDLVSEYQQYQEATADEDAEFEEEQE 450
            ||||||||||||||||||:|||||:.|::||:|
plant   410 TEAESNMNDLVSEYQQYQDATADEEDEYDEEEE 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
betaTub56D	NP_725896.1	beta_tubulin	26..435	CDD:276956	347/406 (85%)
betaTub56D	NP_725896.1	PLN00220	29..438	CDD:215107	349/409 (85%)
TUB1	NP_177706.1	PLN00220	1..431	CDD:215107	350/410 (85%)
TUB1	NP_177706.1	beta_tubulin	2..427	CDD:276956	347/406 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	385	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68504
Inparanoid	1	1.050	798	1.000	Inparanoid score	I89
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	1	1.000	-	-		mtm983
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840